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PROSITE entry PS50860


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PURL: https://purl.expasy.org/prosite/signature/PS50860

Direct ScanProsite submission
General information about the entry

Entry name [info] AA_TRNA_LIGASE_II_ALA
Accession [info] PS50860
Entry type [info] MATRIX
Date [info] 01-MAY-2002 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00363

Name and characterization of the entry

Description [info] Alanyl-transfer RNA synthetases family profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=715;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=710;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.2391000; R2=0.0075110; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=84358.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1699; H_SCORE=84358; N_SCORE=13.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=834; H_SCORE=84358; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Post-processing [info]

COMPETES_SEQ_WITH PS50862

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 729 in 729 different sequences
Number of true positive hits 729 in 729 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.73 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
729 sequences

AASD1_BOVIN (Q32LK1), AASD1_HUMAN (Q9BTE6), AASD1_MOUSE (Q3THG9), 
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UniProtKB/Swiss-Prot
False negative sequences
2 sequences

AASD1_DANRE (Q6DEJ5), YNE0_YEAST  (P53960)

		
PDB
[Detailed view]
25 PDB

1RIQ; 1YFR; 1YFS; 1YFT; 1YGB; 2E1B; 2ZTG; 2ZZE; 2ZZF; 2ZZG; 3HTZ; 3HXU;
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