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PROSITE entry PS50848


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PURL: https://purl.expasy.org/prosite/signature/PS50848

Direct ScanProsite submission
General information about the entry

Entry name [info] START
Accession [info] PS50848
Entry type [info] MATRIX
Date [info] 01-MAY-2002 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50848
Associated ProRule [info] PRU00197

Name and characterization of the entry

Description [info] START domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=215;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=210;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.6883000; R2=0.0245032; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=9495.6386719; R2=9.8773689; PRIORITY=1; TEXT='Heuristic 0.1%';
/CUT_OFF: LEVEL=0; SCORE=381; H_SCORE=13259; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=238; H_SCORE=11846; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 109 in 109 different sequences
Number of true positive hits 109 in 109 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] START
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
109 sequences

ACO11_HUMAN (Q8WXI4), ACO11_MOUSE (Q8VHQ9), ACO12_HUMAN (Q8WYK0), 
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PDB
[Detailed view]
42 PDB

1EM2; 1JSS; 1LN1; 1LN2; 1LN3; 2E3M; 2E3N; 2E3O; 2E3P; 2E3Q; 2E3R; 2E3S;
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