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PROSITE entry PS50846


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PURL: https://purl.expasy.org/prosite/signature/PS50846

Direct ScanProsite submission
General information about the entry

Entry name [info] HMA_2
Accession [info] PS50846
Entry type [info] MATRIX
Date [info] 01-JAN-2002 CREATED;
25-MAY-2022 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00804
Associated ProRule [info] PRU00280

Name and characterization of the entry

Description [info] Heavy-metal-associated domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=67;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=67;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.0176628; R2=0.0089474; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1004; N_SCORE=11.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=501; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-36; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 334 in 237 different sequences
Number of true positive hits 334 in 237 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 7
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] HMA
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
237 sequences

ATCS_SYNE7  (P37279), ATCS_SYNY3  (P73241), ATCU1_RHIME (P58341), 
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PDB
[Detailed view]
113 PDB

1AFI; 1AFJ; 1AW0; 1CC7; 1CC8; 1CPZ; 1DVW; 1FD8; 1FE0; 1FE4; 1FEE; 1FES;
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