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PROSITE entry PS50823


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PURL: https://purl.expasy.org/prosite/signature/PS50823

Direct ScanProsite submission
General information about the entry

Entry name [info] KH_TYPE_2
Accession [info] PS50823
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
03-MAY-2023 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50084
Associated ProRule [info] PRU00118

Name and characterization of the entry

Description [info] Type-2 KH domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=73;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=68;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.7877001; R2=0.0176456; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3049.8864746; R2=3.1439395; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=438; H_SCORE=4427; N_SCORE=9.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=268; H_SCORE=3892; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Post-processing [info]

COMPETES_HIT_WITH PS50084

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 1'254 in 1'254 different sequences
Number of true positive hits 1'254 in 1'254 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 57
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.65 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann, N_Hulo
Feature key [info] DOMAIN
Feature description [info] KH type-2
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
1254 sequences

ERA1_MAIZE  (K7UTH7), ERAL1_DANRE (B0S6U7), ERAL1_SALSA (B5X2B8), 
» more

UniProtKB/Swiss-Prot
False negative sequences
57 sequences

ERAL1_AILME (D2GU20), ERAL1_BOVIN (A5PK43), ERAL1_CHICK (Q8JIF5), 
» more

PDB
[Detailed view]
1366 PDB

1EGA; 1FJG; 1HNW; 1HNX; 1HNZ; 1HR0; 1I94; 1I95; 1I96; 1I97; 1IBK; 1IBL;
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