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PROSITE entry PS50822


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PURL: https://purl.expasy.org/prosite/signature/PS50822

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General information about the entry

Entry name [info] PIWI
Accession [info] PS50822
Entry type [info] MATRIX
Date [info] 01-MAY-2002 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50822
Associated ProRule [info] PRU00150

Name and characterization of the entry

Description [info] Piwi domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=297;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=292;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1406; R2=0.01583904; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=402; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=276; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 86 in 86 different sequences
Number of true positive hits 85 in 85 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 98.84 %
Recall (true positives / (true positives + false negatives)) 98.84 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] Piwi
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
85 sequences

AGO10_ARATH (Q9XGW1), AGO11_ORYSJ (Q10F39), AGO12_ORYSJ (Q7Y001), 
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UniProtKB/Swiss-Prot
False negative sequences
1 sequence

AGO1_LEIBR  (G8XR08)

		
UniProtKB/Swiss-Prot
False positive sequences
1 sequence

VAPB4_METJA (P0CW38)

		
PDB
[Detailed view]
125 PDB

1U04; 1W9H; 1YTU; 1YVU; 1Z25; 1Z26; 2BGG; 2F8S; 2F8T; 2NUB; 2W42; 3DLB;
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