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PROSITE entry PS50817


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PURL: https://purl.expasy.org/prosite/signature/PS50817

Direct ScanProsite submission
General information about the entry

Entry name [info] INTEIN_N_TER
Accession [info] PS50817
Entry type [info] MATRIX
Date [info] 01-MAY-2002 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00687

Name and characterization of the entry

Description [info] Intein N-terminal splicing motif profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=80;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=75;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.8451000; R2=0.0257841; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3172.8544922; R2=3.0545454; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=270; H_SCORE=3998; N_SCORE=7.8; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=220; H_SCORE=3845; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 146 in 133 different sequences
Number of true positive hits 144 in 131 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 6
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 98.63 %
Recall (true positives / (true positives + false negatives)) 96.00 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 3
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
131 sequences

AATA_PYRAB  (Q9UXU7), AATA_PYRFU  (Q8U4A6), AATA_PYRHO  (O57728), 
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UniProtKB/Swiss-Prot
False negative sequences
6 sequences

DNAB_GUITH  (O78411), DNAB_MYCIT  (Q9F5P4), DNAB_MYCLE  (P46394), 
» more

UniProtKB/Swiss-Prot
False positive sequences
2 sequences

ERC6L_DANRE (A2BGR3), HIR1_EREGS  (Q74ZN0)

		
PDB
[Detailed view]
45 PDB

1AM2; 1AT0; 1DFA; 1DQ3; 1GPP; 1LWS; 1LWT; 1MI8; 1VDE; 1ZD7; 1ZDE; 2CW7;
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