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PROSITE entry PS50802


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50802
Entry name [info] OTU
Accession [info] PS50802
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50802
Associated ProRule [info] PRU00139

Name and characterization of the entry

Description [info] OTU domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=128;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=123;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.7570000; R2=0.0212912; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6203.8706055; R2=3.2879465; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=317; H_SCORE=7246; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=223; H_SCORE=6937; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-7; D=-20; I=-20; B1=*; E1=*; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 91 in 91 different sequences
Number of true positive hits 91 in 91 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 8
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 91.92 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] OTU
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
91 sequences

ALG13_HUMAN (Q9NP73), ALG13_MOUSE (Q9D8C3), L_CCHFI (Q6TQR6), 
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UniProtKB/Swiss-Prot
False negative sequences
8 sequences

OTULL_HUMAN (Q9NUU6), OTULL_MOUSE (Q3TVP5), OTULL_RAT   (Q3B7D8), 
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PDB
[Detailed view]
71 PDB

1TFF; 2VFJ; 2ZFY; 3BY4; 3C0R; 3DKB; 3PFY; 3PHU; 3PHW; 3PHX; 3PRM; 3PRP;
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