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PROSITE entry PS50800


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PURL: https://purl.expasy.org/prosite/signature/PS50800

Direct ScanProsite submission
General information about the entry

Entry name [info] SAP
Accession [info] PS50800
Entry type [info] MATRIX
Date [info] 01-FEB-2003 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50800
Associated ProRule [info] PRU00186

Name and characterization of the entry

Description [info] SAP motif profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=35;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=32;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1756001; R2=0.0199757; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1162.7791748; R2=1.5220884; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=317; H_SCORE=1645; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=217; H_SCORE=1493; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=*; E1=*; MI=-105; MD=-105; IM=-105; DM=-105; M0=-8;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 123 in 120 different sequences
Number of true positive hits 123 in 120 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 24
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 83.67 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] SAP
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
120 sequences

049L_FRG3G  (Q6GZS7), ACINU_HUMAN (Q9UKV3), ACINU_MOUSE (Q9JIX8), 
» more

UniProtKB/Swiss-Prot
False negative sequences
24 sequences

C3H62_ORYSJ (Q338N2), DEK_HUMAN   (P35659), DEK_MOUSE   (Q7TNV0), 
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PDB
[Detailed view]
94 PDB

1H1J; 1JEQ; 1JEY; 1JJR; 1KCF; 1V66; 1ZBH; 1ZBU; 1ZRJ; 2DO1; 2DO5; 2JX3;
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