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PROSITE entry PS50304


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PURL: https://purl.expasy.org/prosite/signature/PS50304

Direct ScanProsite submission
General information about the entry

Entry name [info] TUDOR
Accession [info] PS50304
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50304
Associated ProRule [info] PRU00211

Name and characterization of the entry

Description [info] Tudor domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=61;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=56;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.0072000; R2=0.0201488; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2856.1633301; R2=2.1802721; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=273; H_SCORE=3451; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=174; H_SCORE=3236; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=*; E1=*; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 167 in 103 different sequences
Number of true positive hits 163 in 99 different sequences
Number of 'unknown' hits 0
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 66
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 97.60 %
Recall (true positives / (true positives + false negatives)) 71.18 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 9
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] V_Jongeneel
Feature key [info] DOMAIN
Feature description [info] Tudor
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
99 sequences

AKAP1_CAEEL (Q09285), AKAP1_HUMAN (Q92667), AKAP1_MOUSE (O08715), 
» more

UniProtKB/Swiss-Prot
False negative sequences
66 sequences

BOYB_DROME  (Q9VNP5), COIL_ARATH  (Q8RWK8), COIL_HUMAN  (P38432), 
» more

UniProtKB/Swiss-Prot
False positive sequences
4 sequences

NHR61_CAEEL (O62389), U90A1_ARATH (Q9ZVX4), U90A2_ARATH (Q9SY84), 
» more

PDB
[Detailed view]
50 PDB

1G5V; 1MHN; 2D9T; 2DIQ; 2E6N; 2EQK; 2HQE; 2HQX; 2LTO; 2O4X; 2WAC; 3BDL;
» more