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PROSITE entry PS50303


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PURL: https://purl.expasy.org/prosite/signature/PS50303

Direct ScanProsite submission
General information about the entry

Entry name [info] PUM_HD
Accession [info] PS50303
Entry type [info] MATRIX
Date [info] 01-JAN-2004 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50302
Associated ProRule [info] PRU00318

Name and characterization of the entry

Description [info] Pumilio homology domain (PUM-HD) profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=346;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=341;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.0346098; R2=0.0292075; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=26499.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=188; H_SCORE=26499; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=119; H_SCORE=26499; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-50; I=-50; B0=-100; B1=-1000; E0=-100; E1=-1000; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 62 in 62 different sequences
Number of true positive hits 62 in 62 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.88 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] PUM-HD
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
62 sequences

FBF1_CAEEL  (Q9N5M6), FBF2_CAEEL  (Q09312), JSN1_YEAST  (P47135), 
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UniProtKB/Swiss-Prot
False negative sequences
2 sequences

NOP9_YEAST  (P47077), PUM23_ARATH (Q9C552)

		
PDB
[Detailed view]
60 PDB

1IB2; 1M8W; 1M8X; 1M8Y; 1M8Z; 2YJY; 3BSB; 3BSX; 3BWT; 3BX2; 3BX3; 3GVO;
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