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PROSITE entry PS50262


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50262
Entry name [info] G_PROTEIN_RECEP_F1_2
Accession [info] PS50262
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00210
Associated ProRule [info] PRU00521

Name and characterization of the entry

Description [info] G-protein coupled receptors family 1 profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=259;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=254;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.9359; R2=0.02006056; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=328; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=228; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105; MM=1; M0=-10;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 2'547 in 2'545 different sequences
Number of true positive hits 2'493 in 2'491 different sequences
Number of 'unknown' hits 41 in 41 different sequences
Number of false positive hits 13 in 13 different sequences
Number of false negative sequences 12
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 99.48 %
Recall (true positives / (true positives + false negatives)) 99.52 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
2491 sequences

10D1B_MOUSE (Q60888), 10H28_MOUSE (Q8VBW9), 10P22_MOUSE (Q60885), 
» more

UniProtKB/Swiss-Prot
False negative sequences
12 sequences

LGR6_HUMAN  (Q9HBX8), LGR6_MOUSE  (Q3UVD5), MRGRG_MOUSE (Q91ZB5), 
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UniProtKB/Swiss-Prot
'Partial' sequences
3 sequences

GPCR_MOUSE  (P83854), OLF2_APILI  (Q26420), OLF9_APILI  (Q26421)

		
UniProtKB/Swiss-Prot
'Unknown' sequences
41 sequences

T2R13_MOUSE (Q7M720), T2R14_PAPHA (Q646F4), T2R39_MOUSE (Q7TQA5), 
» more

UniProtKB/Swiss-Prot
False positive sequences
13 sequences

COXX_VEREI  (A1WHP5), CRLC_DICDI  (Q6UUW6), CRLD_DICDI  (Q54QV5), 
» more

PDB
[Detailed view]
1321 PDB

1F88; 1FDF; 1GZM; 1HLL; 1HO9; 1HOD; 1HOF; 1HZX; 1JFP; 1L9H; 1LN6; 1U19;
» more