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PROSITE entry PS50261


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PURL: https://purl.expasy.org/prosite/signature/PS50261

Direct ScanProsite submission
General information about the entry

Entry name [info] G_PROTEIN_RECEP_F2_4
Accession [info] PS50261
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00559

Name and characterization of the entry

Description [info] G-protein coupled receptors family 2 profile 2.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=257;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=252;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2047999; R2=0.0128681; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=13571.0966797; R2=8.4188871; PRIORITY=1; TEXT='Heuristic 0.1%';
/CUT_OFF: LEVEL=0; SCORE=645; H_SCORE=19001; N_SCORE=10.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=334; H_SCORE=16383; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105; MM=1; M0=-10;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 288 in 288 different sequences
Number of true positive hits 286 in 286 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 19
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.31 %
Recall (true positives / (true positives + false negatives)) 93.77 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
286 sequences

AGRA1_HUMAN (Q86SQ6), AGRA1_MOUSE (Q8C4G9), AGRA2_DANRE (E7FBY6), 
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UniProtKB/Swiss-Prot
False negative sequences
19 sequences

CRLD_DICDI  (Q54QV5), FSCB_DICDI  (Q54RQ3), FSCC_DICDI  (Q1ZXA7), 
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UniProtKB/Swiss-Prot
False positive sequences
2 sequences

TAAR5_MOUSE (Q5QD14), TAAR5_RAT   (Q5QD23)

		
PDB
[Detailed view]
208 PDB

4JKV; 4K5Y; 4L6R; 4N4W; 4O9R; 4QIM; 4QIN; 4Z9G; 5EE7; 5L7D; 5L7I; 5NX2;
» more