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PROSITE entry PS50249


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50249
Entry name [info] MPN
Accession [info] PS50249
Entry type [info] MATRIX
Date [info] 27-SEP-2017 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50249
Associated ProRule [info] PRU01182

Name and characterization of the entry

Description [info] MPN domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=128;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=123;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.7767394; R2=0.0096091; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=18059.7500000; R2=4.5673075; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1012; H_SCORE=22682; N_SCORE=11.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=700; H_SCORE=21257; N_SCORE=8.5; MODE=1; TEXT='?';
/DEFAULT: M0=-31; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 688 in 688 different sequences
Number of true positive hits 688 in 688 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.57 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] MPN
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
688 sequences

ABRX1_BOVIN (Q5E9P1), ABRX1_CHICK (Q5ZHS0), ABRX1_DANRE (Q1LVP6), 
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UniProtKB/Swiss-Prot
False negative sequences
3 sequences

CAP3_ECOTW  (P0DTF3), CAP3_VIBCH  (Q9KVG5), JAMM1_THET2 (Q72IJ9)

		
PDB
[Detailed view]
320 PDB

2O95; 2O96; 2OG4; 2P87; 2P8R; 2QLC; 2ZNR; 2ZNV; 3J8B; 3J8C; 3JB9; 3JCK;
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