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PROSITE entry PS50231


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50231
Entry name [info] RICIN_B_LECTIN
Accession [info] PS50231
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50231
Associated ProRule [info] PRU00174

Name and characterization of the entry

Description [info] Lectin domain of ricin B chain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=129;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=124;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.6000000; R2=0.0255000; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6188.0952148; R2=4.7309322; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=310; H_SCORE=7655; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=232; H_SCORE=7286; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 211 in 175 different sequences
Number of true positive hits 198 in 162 different sequences
Number of 'unknown' hits 0
Number of false positive hits 13 in 13 different sequences
Number of false negative sequences 5
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 93.84 %
Recall (true positives / (true positives + false negatives)) 97.54 %

Comments [info]

Taxonomic range [info] Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 3
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] DOMAIN
Feature description [info] Ricin B-type lectin
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
162 sequences

ABRA_ABRPR  (P11140), ABRB_ABRPR  (Q06077), ABRC_ABRPR  (P28590), 
» more

UniProtKB/Swiss-Prot
False negative sequences
5 sequences

40C1_ORYSJ  (Q10M12), 40G2_ORYSJ  (Q6Z4N6), 40G3_ORYSJ  (Q6Z4N4), 
» more

UniProtKB/Swiss-Prot
False positive sequences
13 sequences

DCA10_MOUSE (A2AKB9), ENVE_SALTY  (Q56030), MB212_DANRE (Q8UUZ1), 
» more

PDB
[Detailed view]
125 PDB

1ABR; 1CE7; 1DQG; 1DQO; 1FWU; 1FWV; 1KNL; 1KNM; 1M2T; 1MC9; 1ONK; 1OQL;
» more