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PROSITE entry PS50219


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50219
Entry name [info] CNH
Accession [info] PS50219
Entry type [info] MATRIX
Date [info] 01-SEP-2009 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50219
Associated ProRule [info] PRU00795

Name and characterization of the entry

Description [info] Citron homology (CNH) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=279;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=274;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.6258330; R2=0.0039226; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=42619.5273438; R2=12.3632212; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=2390; H_SCORE=72168; N_SCORE=11.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1243; H_SCORE=57987; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-16; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 56 in 56 different sequences
Number of true positive hits 56 in 56 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] CNH
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
56 sequences

CTRO_HUMAN  (O14578), CTRO_MOUSE  (P49025), CTRO_RAT(E9PSL7), 
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PDB
[Detailed view]
3 PDB

7Z6E; 8EEC; 8QX8