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PROSITE entry PS50211


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50211
Entry name [info] DENN
Accession [info] PS50211
Entry type [info] MATRIX
Date [info] 01-DEC-2003 CREATED;
05-JUL-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50211
Associated ProRule [info] PRU00304

Name and characterization of the entry

Description [info] Tripartite DENN domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=430;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=425;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4746370; R2=0.0072344; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1248; N_SCORE=11.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=557; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-20; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 71 in 71 different sequences
Number of true positive hits 71 in 71 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] uDENN
Feature key [info] DOMAIN
Feature description [info] cDENN
Feature key [info] DOMAIN
Feature description [info] dDENN
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
71 sequences

AFI1_YEAST  (Q99222), ANR2_YEAST  (P36090), AVL9_HUMAN  (Q8NBF6), 
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PDB
[Detailed view]
3 PDB

3TW8; 6EKK; 8P0V