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PROSITE entry PS50202


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PURL: https://purl.expasy.org/prosite/signature/PS50202

Direct ScanProsite submission
General information about the entry

Entry name [info] MSP
Accession [info] PS50202
Entry type [info] MATRIX
Date [info] 01-OCT-2002 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50202
Associated ProRule [info] PRU00132

Name and characterization of the entry

Description [info] Major sperm protein (MSP) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=120;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=115;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.9481000; R2=0.0218566; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=5708.1264648; R2=3.5768194; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=300; H_SCORE=6781; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=209; H_SCORE=6456; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-1000; E1=-1000; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 72 in 71 different sequences
Number of true positive hits 72 in 71 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] MSP
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
71 sequences

CFA65_HUMAN (Q6ZU64), MS152_CAEEL (Q23519), MSP10_CAEEL (P05634), 
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UniProtKB/Swiss-Prot
False negative sequences
3 sequences

CFA65_CHICK (F1P4W9), CFA65_CHLRE (A8JFU2), CFA65_MOUSE (Q3V0B4)

		
PDB
[Detailed view]
22 PDB

1GRW; 1M1S; 1MSP; 1ROW; 1WIC; 1Z9L; 1Z9O; 2BVU; 2CRI; 2MDK; 2MSP; 2RR3;
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