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PROSITE entry PS50195


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PURL: https://purl.expasy.org/prosite/signature/PS50195

Direct ScanProsite submission
General information about the entry

Entry name [info] PX
Accession [info] PS50195
Entry type [info] MATRIX
Date [info] 01-MAY-2002 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50195
Associated ProRule [info] PRU00147

Name and characterization of the entry

Description [info] PX domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=116;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=111;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.7983999; R2=0.0146237; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=5771.9018555; R2=3.3948598; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=390; H_SCORE=7096; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=254; H_SCORE=6634; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-1000; E1=-1000; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 246 in 246 different sequences
Number of true positive hits 246 in 246 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 14
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 94.62 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] PX
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
246 sequences

ATG20_CANAL (Q59TN9), ATG20_CANGA (Q6FR93), ATG20_DEBHA (Q6BZE1), 
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UniProtKB/Swiss-Prot
False negative sequences
14 sequences

MU122_SCHPO (O74444), PLD1_SCHPO  (Q09706), PLDZ1_ARATH (Q9LRZ5), 
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PDB
[Detailed view]
82 PDB

1GD5; 1H6H; 1KMD; 1KQ6; 1O7K; 1OCS; 1OCU; 1XTE; 1XTN; 2AR5; 2CSK; 2CZO;
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