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PROSITE entry PS50191


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PURL: https://purl.expasy.org/prosite/signature/PS50191

Direct ScanProsite submission
General information about the entry

Entry name [info] CRAL_TRIO
Accession [info] PS50191
Entry type [info] MATRIX
Date [info] 01-JUN-2002 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50191
Associated ProRule [info] PRU00056

Name and characterization of the entry

Description [info] CRAL-TRIO lipid binding domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=167;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=162;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.2046000; R2=0.0139792; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=10036.2558594; R2=6.3555093; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=558; H_SCORE=13583; N_SCORE=8.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=451; H_SCORE=12903; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-6; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 160 in 160 different sequences
Number of true positive hits 160 in 160 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 8
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.24 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] CRAL-TRIO
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
160 sequences

ATCAY_HUMAN (Q86WG3), ATCAY_MACFA (Q9GKT0), ATCAY_MOUSE (Q8BHE3), 
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UniProtKB/Swiss-Prot
False negative sequences
8 sequences

GDAP2_BOVIN (Q2KIX2), GDAP2_DANRE (Q66HX8), GDAP2_HUMAN (Q9NXN4), 
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PDB
[Detailed view]
65 PDB

1AUA; 1O6U; 1OIP; 1OIZ; 1OLM; 1R5L; 2D4Q; 2E2X; 3B74; 3B7N; 3B7Q; 3B7Z;
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