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PROSITE entry PS50181


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PURL: https://purl.expasy.org/prosite/signature/PS50181

Direct ScanProsite submission
General information about the entry

Entry name [info] FBOX
Accession [info] PS50181
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50181
Associated ProRule [info] PRU00080

Name and characterization of the entry

Description [info] F-box domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=47;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=43;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.8338000; R2=0.0264944; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1530.4213867; R2=2.3578596; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=290; H_SCORE=2214; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=214; H_SCORE=2035; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-80; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105; MM=1;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 655 in 655 different sequences
Number of true positive hits 654 in 654 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 467
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.85 %
Recall (true positives / (true positives + false negatives)) 58.34 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] DOMAIN
Feature description [info] F-box
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
654 sequences

AARA_DICDI  (Q54I71), ADLO2_ARATH (Q9M224), ADO1_ARATH  (Q94BT6), 
» more

UniProtKB/Swiss-Prot
False negative sequences
467 sequences

ADLO1_ARATH (O22161), ADO1_ORYSJ  (Q5Z8K3), ADO2_ARATH  (Q8W420), 
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UniProtKB/Swiss-Prot
False positive sequences
1 sequence

FLIG_AQUAE  (O66891)

		
PDB
[Detailed view]
86 PDB

1FQV; 1FS1; 1FS2; 1LDK; 1NEX; 1P22; 2ASS; 2AST; 2E31; 2E32; 2OVP; 2OVQ;
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