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PROSITE entry PS50177


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PURL: https://purl.expasy.org/prosite/signature/PS50177

Direct ScanProsite submission
General information about the entry

Entry name [info] NTF2_DOMAIN
Accession [info] PS50177
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50177
Associated ProRule [info] PRU00137

Name and characterization of the entry

Description [info] Nuclear transport factor 2 domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=119;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=114;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.5280000; R2=0.0199639; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=5175.7641602; R2=7.5756822; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=400; H_SCORE=8206; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=300; H_SCORE=7448; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 61 in 61 different sequences
Number of true positive hits 60 in 60 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 98.36 %
Recall (true positives / (true positives + false negatives)) 98.36 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann, N_Hulo
Feature key [info] DOMAIN
Feature description [info] NTF2
Version [info] 7

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
60 sequences

BRE5_YEAST  (P53741), G3BP1_BOVIN (Q32LC7), G3BP1_HUMAN (Q13283), 
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UniProtKB/Swiss-Prot
False negative sequences
1 sequence

NXF5_HUMAN  (Q9H1B4)

		
UniProtKB/Swiss-Prot
False positive sequences
1 sequence

CATEA_XENLA (Q805F3)

		
PDB
[Detailed view]
43 PDB

1AR0; 1ASK; 1GY5; 1GY6; 1GY7; 1GYB; 1JB2; 1JB4; 1JB5; 1JKG; 1JN5; 1OF5;
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