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PROSITE entry PS50160


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50160
Entry name [info] DNA_LIGASE_A3
Accession [info] PS50160
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00295

Name and characterization of the entry

Description [info] ATP-dependent DNA ligase family profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=135;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=130;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.4573000; R2=0.0139318; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6808.7558594; R2=10.2896852; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=578; H_SCORE=12756; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=434; H_SCORE=11274; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 179 in 179 different sequences
Number of true positive hits 178 in 178 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.44 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
178 sequences

DNLI1_ARATH (Q42572), DNLI1_CAEEL (Q27474), DNLI1_DICDI (Q869E1), 
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UniProtKB/Swiss-Prot
False positive sequences
1 sequence

KDGR_BACSU  (P50844)

		
PDB
[Detailed view]
54 PDB

1A0I; 1VS0; 1X9N; 2CFM; 2HIV; 2HIX; 3GDE; 3L2P; 3VNN; 3W1B; 3W1G; 3W5O;
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