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PROSITE entry PS50156


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50156
Entry name [info] SSD
Accession [info] PS50156
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50156
Associated ProRule [info] PRU00199

Name and characterization of the entry

Description [info] Sterol-sensing domain (SSD) profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=159;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=154;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.3390000; R2=0.0174703; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6457.8911133; R2=16.8936710; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=410; H_SCORE=13384; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=296; H_SCORE=11458; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-70; E1=-70; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 119 in 115 different sequences
Number of true positive hits 86 in 86 different sequences
Number of 'unknown' hits 32 in 28 different sequences
Number of false positive hits 1
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 98.85 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] DOMAIN
Feature description [info] SSD
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
86 sequences

DISP1_DANRE (Q6R5J2), DISP1_HUMAN (Q96F81), DISP1_MOUSE (Q3TDN0), 
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UniProtKB/Swiss-Prot
'Unknown' sequences
28 sequences

APEX_BACAN  (Q81QL7), MMPL3_MYCTO (P9WJV4), MMPL3_MYCTU (P9WJV5), 
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UniProtKB/Swiss-Prot
False positive sequences
1 sequence

SECDF_THET8 (Q5SKE6)

		
PDB
[Detailed view]
54 PDB

3JD8; 5JNX; 5KHS; 5U73; 5U74; 6DMB; 6DMO; 6DMY; 6E1H; 6M49; 6MG8; 6N7G;
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