PROSITE entry PS50151

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS50151
Entry name [info]	UVR
Accession [info]	PS50151
Entry type [info]	MATRIX
Date [info]	01-APR-2002 CREATED; 13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC50151
Associated ProRule [info]	PRU00217

Name and characterization of the entry

Description [info]

UVR domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=36;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=33;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.4512000; R2=0.0155257; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1579.0720215; R2=1.5585586; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=442; H_SCORE=2268; N_SCORE=8.3; MODE=1;
/CUT_OFF: LEVEL=-1; SCORE=326; H_SCORE=2087; N_SCORE=6.5; MODE=1;
/DEFAULT: M0=-7; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;

...

                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='E';  M= -6, 13,-27, 18, 23,-29,-14, -4,-26,  9,-21,-16,  6, -8, 10,  2, -1, -8,-23,-29,-17, 16;
/M: SY='E';  M= -1,  2,-25,  3, 17,-27,-15, -6,-24, 16,-21,-12,  1, -9, 13, 10,  1, -4,-19,-25,-15, 15;
/M: SY='L';  M= -8,-14,-22,-14, -2, -6,-25,-11,  1, -7,  4,  2,-14,-19, -5, -5, -9, -4,  2,-21, -2, -4;
/M: SY='I';  M= -8,-28,-24,-34,-25,  2,-34,-23, 33,-26, 25, 18,-23,-24,-19,-23,-20, -8, 23,-21, -1,-24;
/M: SY='K';  M= -4,  6,-26,  6, 10,-26,-15, -5,-24, 15,-21,-13,  5, -9,  6, 12, -2, -6,-19,-26,-15,  7;
/M: SY='E';  M= -8,  6,-26,  8, 16,-26,-17,  6,-23, 10,-20,-10,  4,-11, 14,  5, -2, -7,-21,-26,-10, 14;
/M: SY='L';  M= -6,-26,-20,-29,-20,  7,-28,-18, 18,-25, 35, 17,-25,-27,-18,-19,-22, -6, 11,-18,  3,-20;
/M: SY='E';  M= -9,  1,-26,  4, 24,-22,-21, -5,-19,  8,-15,-11, -2, -9, 10,  4, -1, -2,-17,-26,-12, 17;
/M: SY='K';  M= -5, -1,-26, -1, 13,-24,-16, -4,-23, 18,-19, -9,  0,-11, 12, 12, -4, -8,-19,-23,-12, 13;
/M: SY='E';  M= -2, -2,-26, -1, 15,-26,-18, -5,-19, 12,-15, -8, -4,-10, 15,  6, -3, -7,-17,-23,-13, 14;
/M: SY='M';  M=-10,-15,-24,-22,-11, -8,-22, -6,  9,  2,  8, 35,-14,-17,  0, -3,-17,-10,  3,-21, -3, -6;
/I:         I=-6; MD=-32;
/M: SY='E';  M=-11,  1,-27,  2, 14,-18,-19,  3,-17,  5,-13, -7,  0,-13, 10,  1, -6, -8,-19,-18, -3, 11; D=-6;
/I:         I=-6; MI=-32; IM=-32; DM=-32;
/M: SY='E';  M= -7,  1,-27,  4, 24,-28,-19, -3,-24, 16,-21,-11, -1, -8, 20, 12,  0, -5,-21,-25,-14, 22;
/M: SY='A';  M= 34,-13,-10,-21,-12,-11, -7,-16, -7,-13, -3, -6,-13,-15,-12,-19,  3, -2,  0,-19,-12,-12;
/M: SY='A';  M= 22,-12,-13,-18,-13,-14,-10,-20,  1,-14, -9, -6, -8,-14,-11,-18, 12,  7,  8,-27,-15,-13;
/M: SY='R';  M= -7,  3,-26,  4, 13,-28,-12,  0,-26, 14,-23,-12,  4,-12, 15, 17,  0, -7,-22,-26,-14, 13;
/M: SY='N';  M=  0, 14,-22, 12, 12,-26, -8, -3,-22,  1,-22,-15, 15,-11,  7, -4,  7, -1,-20,-31,-18, 10;
/M: SY='L';  M=-11,-15,-24,-16, -2, -6,-22, -5,  0,-12, 14, 11,-14,-20,  7, -8,-16,-10, -8,-18, -3,  3;
/M: SY='D';  M=-12, 18,-28, 24, 23,-30,-15,  1,-29, 12,-24,-16, 11,-10, 13,  9, -1, -9,-26,-30,-16, 18;
/M: SY='F';  M=-20,-28,-22,-37,-28, 72,-30,-14,  0,-27,  8,  0,-20,-30,-35,-18,-20,-10, -2, 13, 38,-28;
/M: SY='E';  M=-10, 12,-30, 22, 57,-30,-19,  0,-30,  9,-21,-20,  2, -1, 19,  0,  0,-10,-30,-31,-20, 38;
/M: SY='E';  M= -8,  1,-26,  3, 15,-24,-18, -2,-22, 14,-15,-10,  0,-12, 10, 12, -5, -7,-19,-25,-12, 11;
/M: SY='A';  M= 48,-10, -7,-20,-11,-20, -1,-20,-11,-11,-10,-10,-10,-11,-11,-20,  9,  0,  0,-21,-20,-11;
/M: SY='A';  M= 32,-12,-15,-19, -9,-18, -4,-19, -7, -9, -7, -6,-10,-12, -9,-15,  4, -3, -1,-21,-17,-10;
/M: SY='Q';  M= -6, -4,-26, -4,  8,-20,-17,  8,-19,  7,-16, -7, -1,-14, 10, 10, -3, -7,-17,-23, -6,  7;
/M: SY='L';  M=-13,-28,-24,-31,-24, 20,-32,-15, 21,-26, 26, 13,-24,-28,-21,-20,-24,-10, 11, -7, 20,-24;
/M: SY='R';  M=-20,-11,-30,-11, -2,-16,-21,  1,-26, 25,-16, -8, -2,-21,  8, 61,-11,-10,-18,-17, -4, -2;
/M: SY='D';  M=-17, 43,-29, 60, 18,-38,-10, -1,-38,  2,-28,-28, 18,-11,  1, -5,  0,-10,-28,-38,-19,  9;
/M: SY='Q';  M= -9, -5,-25, -3,  9,-20,-18, -5,-16,  4, -8, -4, -5,-15, 12, 10, -5, -4,-15,-23, -9,  9;
/M: SY='I';  M=-10,-21,-27,-24, -9, -5,-32,-19, 23,-20, 18, 15,-18,-19, -8,-19,-18,-10, 11,-22, -4,-11;
/M: SY='Q';  M= -4, -7,-23,-13, -5,-13,-17, -7, -7,  1, -8,  1, -3,-16,  3, -1, -4, -2, -8,-22, -7, -2;
/M: SY='E';  M=  5, -1,-22, -1, 12,-22,-14, -4,-18,  3,-12,-10, -3,-11,  6, -2,  0, -5,-15,-24,-12,  8;
/M: SY='L';  M= -7,-29,-18,-32,-23,  5,-31,-23, 26,-28, 33, 16,-26,-27,-21,-22,-23, -8, 18,-21, -1,-23;
/M: SY='R';  M=-11, -4,-28, -3,  8,-25,-13, -6,-26, 25,-21,-10, -1,-14, 10, 29, -6, -9,-19,-22,-13,  8;
/M: SY='E';  M=  0,  2,-22,  1, 16,-24,-15, -6,-21, 10,-19,-12,  1,-10,  9,  6,  1, -4,-17,-26,-14, 12;
/M: SY='Q';  M= -5, -9,-23,-10,  4,-17,-21, -8, -5, -3,  0,  2, -9,-16,  9, -2, -7, -5, -6,-24, -9,  6;
/I:         E1=0; IE=-105; DE=-105;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	993 in 993 different sequences
Number of true positive hits	992 in 992 different sequences
Number of 'unknown' hits	0
Number of false positive hits	1
Number of false negative sequences	40
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	99.90 %
Recall (true positives / (true positives + false negatives))	96.12 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	window20_shuffled
Author [info]	N_Hulo
Feature key [info]	DOMAIN
Feature description [info]	UVR
Version [info]	6

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	992 sequences CLPAA_SOLLC (P31541), CLPAB_SOLLC (P31542), CLPA_BRANA (P46523), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	40 sequences BBD1_ARATH (Q9FWS6), BBD1_ORYSI (B8A8D2), BBD1_ORYSJ (Q5N8J3), » more
UniProtKB/Swiss-Prot False positive sequences	1 sequence SYC_STRR6 (Q8DQS8)
PDB [Detailed view]	26 PDB 1C4O; 1D2M; 1D9X; 1D9Z; 1E52; 1QOJ; 1T5L; 2D7D; 2FDC; 2NMV; 3J3R; 3J3S; » more