PROSITE entry PS50146

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS50146
Entry name [info]	DAGK
Accession [info]	PS50146
Entry type [info]	MATRIX
Date [info]	01-JUN-2009 CREATED; 13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC50146
Associated ProRule [info]	PRU00783

Name and characterization of the entry

Description [info]

DAG-kinase catalytic (DAGKc) domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=138;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=133;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2304671; R2=0.0085744; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=21680.8535156; R2=4.2508163; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=930; H_SCORE=25634; N_SCORE=10.2; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=498; H_SCORE=23798; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-38; D=-100; I=-100; B1=-350; E1=-350; MI=-105; MD=-105; IM=-105; DM=-105;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-105; BD=-105;
/M: SY='M';  M= -21, -98, -83,  16, -43, -28, -28, -87,  11, -87,  67,  -8,  59, -78, -32,  13,  16, -41,-103, -90;
/M: SY='R';  M= -31,  10,  15, -27, -95, -28, -14, -42,  -8, -38,  10, -23,  20,  -1,  65,  -7,  -7, -21,-103, -88;
/M: SY='M';  M=  -1, -26, -35,  -3, -16, -54,  -7, -38, -19, -27,  64,  18,  58, -31,  -9,  22,   2,  -6,  20, -45;
/M: SY='R';  M= -42,  47, -43, -70, -93, -48,   1, -48,  59, -90, -81, -73,  46, -22,  64,   2,  -6, -20, -96, -84;
/M: SY='P';  M= -31, -95, -34, -50, -22, -60,  40, -58,  54, -50, -81, -15,  61, -67,  50,  20, -13, -41, -95, -80;
/M: SY='L';  M=  42, -86, -95, -89, -24, -48, -90,  36, -89,  48,  -5, -89, -92, -85, -91, -10, -13,  26,  28, -75;
/M: SY='L';  M= -27, -89, -91, -28,  23, -95, -13,   0,  -8,  63,   4, -86, -94, -78,  33, -15,   4, -65,  10, -69;
/M: SY='V';  M= -44, -86,-101, -95,  -1,-102, -96,  23, -94,  47, -55, -97, -98, -93, -94, -87, -73,  82, -95, -73;
/M: SY='I';  M= -84, -90,-103, -99,  71,-104, -93,  73, -96,  40, -55, -96, -97, -95, -96, -92, -79,  14, -80, -60;
/M: SY='L';  M= -40, -89,-100, -94, -26,-101,  -9,  49, -90,  52,   6, -95, -97, -88, -23, -89, -77,  50,  46,  10;
/M: SY='N';  M= -22, -86, -55, -74, -93, -70,  64, -94, -67, -98, -85, 122, -90, -67, -74, -63, -66, -95,-114, -83;
/I:         I=-26; MD=-27;
/M: SY='P';  M= -91,-115, -94, -31,-111, -17, -98, -99, -51, -73, -98, -97, 105, -93,-101,   5, -86, -34,-109,-108; D=-26;
/I:         I=-26; MI=-27; MD=-27; IM=-27; DM=-27;
/M: SY='K';  M= -29,-104,  -7, -21,  11, -98,  18, -24,  60, -97, -91,   2, -97, -15,  11, -11, -36, -50,-104, -87; D=-26;
/I:         I=-26; DM=-27;
/M: SY='S';  M=  34, -97, -91, -91,-107,  31, -94,-104, -91,-106, -99, -81,  -2, -85, -96,  69, -76, -96,-108,-101; D=-26;
/I:         I=-26; DM=-27;
/M: SY='G';  M= -36,  18, -81, -90, -99, 100,  -3,-106, -27,-102, -91,  -8, -86, -83, -90, -67, -84, -99, -93, -93;
/M: SY='K';  M= -49, -92, -14, -67, -96,  33,  -8, -96,  85, -95, -85,  21, -82, -20,  -3, -20,  21, -91, -94, -85;
/M: SY='G';  M= -15, -91, -74, -24, -95,  57, -13, -93,  34, -59,  17,  37, -85,  40,   8,  15, -19, -90, -95, -85;
/M: SY='Q';  M=  35, -91, -23,  -9, -29, -29, -74, -88,  33, -50,  18,  16, -86,  59,  55, -50,  -6, -84, -93, -81;
/M: SY='G';  M=  35,  11,   6, -30, -32,  68, -85, -39, -83, -14, -25, -40, -87, -26, -88,  10, -28, -45,  28, -85;
/M: SY='N';  M= -48, -90,  17,  15, -15, -40,  12, -19,  46, -14, -78,  65, -86, -32, -13,   2, -25,  -3,  15, -79;
/M: SY='K';  M= -77, -94,  13,  13, -94, -40,  -5, -89,  60, -66, -20,  -2,   9,  34,  40,   4,  16, -22, -97, -83;
/M: SY='I';  M= -10, -91,  23,  33, -13, -92, -84,  43, -80,  34, -64, -82, -27,  24, -84,  -4, -75,  17,  15, -76;
/M: SY='W';  M= -34,  -7,-102, -95,  58, -99, -89,  21, -92,  56, -58, -97, -26, -91, -47, -90, -81,  16,  75,  15;
/M: SY='R';  M= -81, -18,  -7,  34, -90, -10,  15, -93,  28, -31,  -8,  -9,   3,  33,  75, -76, -80, -91,  -4, -14;
/M: SY='K';  M= -19, -91,  30,  50, -94, -30, -75, -89,  55, -42, -83,  11, -81, -13,   3,  16,  18, -25, -98, -85;
/M: SY='F';  M=  42, -87, -85, -35,  47, -85,  -9,  15,  14,   8, -68,  18, -91, -78,  11, -22, -74,  16, -87, -70;
/M: SY='V';  M=  19, -12, -84, -23, -82, -21,   3,  10,  30, -30, -69, -26, -89,   7,   9,  -9, -72,  61, -98, -81;
/M: SY='R';  M=  14, -94, -23,  26, -82,  -5, -16,   8,  11, -14,   4, -42,  11,  20,  38, -33, -11, -78,  36,  17;
/I:         I=-30; MD=-32;
/M: SY='P';  M=  -3,-106,  -9, -15, -93, -28,  20, -32, -41,  10, -84, -54,  71, -86,   2, -87, -15, -89,-103,  -4; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='L';  M= -82,   8,-100, -92, -17,-102, -89,  44, -14,  69,  31, -95, -97, -37, -49, -91, -79,  10,  28, -71;
/I:         I=-28; MD=-29;
/M: SY='F';  M=-116,-117, -38,-120,  54,-130,-113, -40,-121,  40, -84,-122,-129, -34,-120,-120,-110, -92,-105, -84; D=-28;
/I:         I=-28; MI=-29; MD=-29; IM=-29; DM=-29;
/M: SY='R';  M= -41,-107, -88,   9,-103,-100,  39, -35,  12, -55, -92, -84, -99, -76,  65,  24, -29, -47,-110, -92; D=-28;
/I:         I=-28; DM=-29;
/M: SY='N';  M=  -9, -91,  37,  48, -87, -54,  32, -83,   0,  13, -77,  65, -86, -67,   0, -33, -74, -20,  18, -81;
/M: SY='P';  M=  66, -89, -48,  -5, -96, -37,  -7, -44, -74, -90, -82, -49,  68,  26, -17,  25, -71, -80, -95, -88;
/I:         I=-22; MD=-23;
/M: SY='G';  M= -25, -94, -79,  -5, -93,  70,  36, -92,   0,  -9, -82,  12, -89, -75,  28, -13, -81, -26, -97, -86; D=-22;
/I:         I=-22; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='Q';  M= -36,  20, -32, -17, -82, -96,  36,  36, -80, -23, -28, -83, -94,  71, -45, -12, -79,  34,  42,  -5; D=-22;
/I:         I=-22; DM=-23;
/M: SY='Q';  M= -78, -94,  31,  21, -31, -91, -14,  -7,  18, -81, -78, -16,  -6,  49, -75,   4,  19,  39,-102, -83; D=-22;
/I:         I=-22; DM=-23;
/M: SY='F';  M= -82,  -5, -99, -96,  59,-101, -91,  39, -93,  28,  17, -91, -96, -93, -94, -84,  34,  38, -85,  -4; D=-22;
/I:         I=-22; DM=-23;
/M: SY='D';  M= -20, -95,  85,  37, -97, -84,  53, -41,  24, -92, -86,  -5, -83,  -4, -27, -35, -13, -26,-107, -82;
/M: SY='V';  M= -42, -86, -99, -93,  -1,-101, -93,  31, -40,  40, -56, -94, -96, -91, -91, -85, -19,  76, -92,   3;
/I:         I=-26; MD=-27;
/M: SY='R';  M=  -5, -94, -88, -13, -85, -95, -86,  30, -32, -77,   3, -82, -92, -76,  64, -15,  40,  23, -99, -21; D=-26;
/I:         I=-26; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='V';  M= -43, -91, -44, -33, -77, -94, -86,   6,  22,  14, -17, -20, -26,  23, -80,   6, -19,  57, -96,   6; D=-26;
/I:         I=-26; DM=-27;
/M: SY='T';  M= -28,  -3, -76, -75, -87, -84, -82, -78,  16, -52,  -3, -10,   4,  -5, -76,   2, 100, -46,-102, -83;
/M: SY='W';  M= -80, -99,  27,  52, -85,  21, -81, -96,  19, -92, -14,  -5, -84,  17,  11, -75,  -1, -95, 118, -73;
/M: SY='E';  M= -76, -97, -25,  57, -86,  51,   1, -98,  15, -93, -85,  -9, -22, -20,  44, -29, -80, -94, -86,  42;
/M: SY='P';  M=  36, -94,  -8,   3, -94,   0, -36, -40,  14, -50, -81, -77,  78,  35, -77,   1, -74, -25, -94, -42;
/M: SY='G';  M=   8, -92,  20,  19, -96,  66, -18, -40,   4, -61, -86,  37, -85, -22,  14, -68, -42, -90, -96, -88;
/M: SY='H';  M= -48, -97,  82,  -1, -37, -85,  96, -94, -31, -59, -19, -61,   8,  37, -74, -32,  -8, -55,-108, -74;
/M: SY='A';  M=  84,  -2, -86, -82, -89,  38, -87, -41, -83, -12,  17, -78, -86, -79, -87, -63, -28, -72, -93, -87;
/M: SY='L';  M= -24, -91, -82,  24, -19, -44, -81,   3,  38,  38, -65, -82, -30,  10,  28, -80, -32,  19, -90, -17;
/M: SY='R';  M=  -6, -95,   9,  48, -43, -87,  56, -93,  18, -27, -80, -33, -84,  18,  66,   0, -36, -89, -97, -78;
/M: SY='L';  M= -23, -89, -97, -40,  23, -99, -82,  35, -89,  58,  49, -93, -96, -85, -39, -87, -26,   6, -80,  45;
/M: SY='V';  M=  35,  24, -95, -91,  45, -25, -91,  21, -89,  -9,  23, -87, -93, -89, -91, -77,   7,  56, -88, -24;
/M: SY='R';  M=  -3,   6,   6,  32, -34,  -3, -75, -89,  41, -89, -82, -21, -85,  27,  45,   5,  -6, -20, -91,   9;
/I:         I=-22; MD=-23;
/M: SY='E';  M= -10, -96,  25,  67,-100, -11, -76, -99,  33, -96, -89,  -3, -82,  -1,  21,  -9,  12, -92,-101, -90; D=-22;
/I:         I=-22; MD=-23;
/M: SY='A';  M=  56,   0, -98, -29,   4, -91, -94,  -6, -93,  27,  -6, -95, -98, -90, -95, -40, -81,  17, -96, -17; D=-22;
/I:         I=-22; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='D';  M= -27,  -7,  45,  11, -80, -21,  15,  15, -49,  27,  -8,  24, -10, -76, -34,   0, -13,  10,-100, -80;
/M: SY='A';  M=  33, -89,   5,  10, -82, -85,  -9,  19, -16,  22,  15,  11,  10,  22,  -7, -73,  13, -35, -96, -81;
/M: SY='Q';  M=   7,   4,  39,  27,   8, -15,  29, -87, -12,  -3, -78,  -6,  16,  51, -75,  15, -75, -85, -93, -21;
/I:         I=-19; MD=-19;
/M: SY='G';  M= -60, -96, -17,  17,   5,  43,  26, -95,  29, -36, -85,  28, -89,   7, -76,  10, -24, -93, -93,  13; D=-19;
/I:         I=-19; MD=-19;
/M: SY='Y';  M= -17,  -8, -98, -94,   5,-101,  38, -19, -90, -80, -78, -93,  10, -13, -34, -87,   4,  35,  52,  71; D=-19;
/I:         I=-19; MD=-19;
/M: SY='D';  M= -18,-106,  92,   7,-112, -42,  19,-111, -45,-109,-104, -69, -94, -43, -46,   0, -48,-106,-122, -96; D=-19;
/I:         I=-19; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='R';  M= -11, -89, -82, -79,   9,  15,   2, -23, -66, -14,  -9, -22, -88, -10,  64,   0,  54, -10, -93, -76;
/M: SY='I';  M= -78, -89,-102, -97, -66,-105, -99,  76, -95,  38, -53, -96, -95, -93, -96, -89, -74,  64, -95, -75;
/M: SY='I';  M=   5, -89, -98, -94, -23, -35, -93,  67, -92,  38, -57, -93,  -2, -90, -94, -85, -75,  44, -90,  -2;
/M: SY='C';  M=  58,  68, -93, -88,  -7, -20, -94,  19, -88, -40, -69, -85, -92, -87, -91, -33, -30,  57, -97, -81;
/M: SY='C';  M=  28,  89, -93, -92, -81,  35, -94,  19, -90, -11,   4, -84, -93, -89, -93, -39, -75,  47, -99, -85;
/M: SY='G';  M= -66, -93,  -6, -88, -99,  99, -86,-106, -85,-102, -93, -66, -85, -81, -92,  28, -79, -99, -93, -93;
/M: SY='G';  M= -67, -94, -82, -94,-100, 106, -89,-108, -87,-104, -93, -68, -86, -85, -95, -67, -86,-102, -91, -95;
/M: SY='D';  M= -84, -98, 121, -49,-105, -81, -71,-103, -72,-102,-101, -53, -84, -71, -81, -13, -74,-100,-120, -88;
/M: SY='G';  M= -67, -94, -82, -94,-100, 106, -89,-108, -87,-104, -93, -68, -86, -85, -95, -67, -86,-102, -91, -95;
/M: SY='T';  M= -71, -82, -80, -82, -19, -21, -85,  -1, -79,  12,  -1, -70, -82, -80, -85,  17, 100, -66, -99, -79;
/M: SY='V';  M=   9, -87, -99, -93,  27, -97, -92,  42, -92,  42,  27, -94,  -3, -90, -93, -85, -75,  54, -90, -71;
/M: SY='H';  M= -74, -91, -68, -76, -92,  47,  78, -98, -69, -96, -84,  76, -87,   2,  23,  35, -72, -96,-101, -19;
/M: SY='W';  M= -13, -99,  20,  85, -87,  -9,  14, -97, -26, -92, -89, -76, -80, -15, -75, -76, -19, -94, 114, -74;
/M: SY='V';  M=   6,  -4, -98, -93,  -5, -97, -99,  36, -91, -35, -61, -92, -94, -92, -93, -80,  -7,  89, -99, -77;
/M: SY='A';  M=  49,   2, -95, -89, -23, -89, -91,  37, -89,  47, -59, -90, -93, -86, -91, -37, -38,  36, -93, -77;
/M: SY='N';  M=  -7, -88,   3,  22, -95,   3,  26, -93, -31, -95, -85,  81,  16,   8, -76,  18,  30, -89,-104, -86;
/M: SY='G';  M=  61, -19, -83, -45, -92,  72, -87, -87, -83, -19, -81, -74, -85, -19, -88, -42,   2, -47, -93, -90;
/M: SY='L';  M= -83, -89,-102, -95, -60,-103, -87,  39, -94,  79,  37, -99, -99, -88, -93, -93, -80,  -8,  32,  -7;
/M: SY='M';  M=  21, -89,  44, -24,   8, -29, -81,  30, -83,  22,  50, -78, -89, -11, -86,   0, -29,  -9, -90,   7;
/M: SY='E';  M=   5, -93, -26,  58, -92, -28,  23, -89,  15, -10, -79,   4, -83,  44,  41,   2, -31, -59, -96, -82;
/M: SY='R';  M=   3, -30, -78, -75, -35, -25,  15,  -2, -30,   3,  11,  42, -90,  27,  71, -27,   1, -55, -95, -78;
/M: SY='P';  M=  -3, -95,  32,  33, -97,  28, -77, -94, -29, -52, -86,  20,  63, -26,  28, -34,   8, -90, -99, -90;
/I:         I=-12; MD=-13;
/M: SY='D';  M= -14,-102,  53, -10,   2, -27,  22, -37, -20,  -3, -84,  -8, -37,  29, -86, -43, -85,  -6,   8, -29; D=-12;
/I:         I=-12; MD=-13;
/M: SY='W';  M= -70,-110, -16,  12, -32, -69,  15, -53,  29, -27, -91, -38,  26, -18,   4, -29, -47, -23,  51,   4; D=-12;
/I:         I=-12; MD=-13;
/M: SY='E';  M=   4,-111, -30,  41,-110,  -9, -31, -99,   3, -27, -99, -24,-105, -89, -95, -35, -96,   0,-119,-107; D=-12;
/I:         I=-12; MD=-13;
/M: SY='Q';  M=   1,-119,  -2,   5,-118, -67,  12, -48, -40, -35,-105,  -9, -21,  15, -25, -14,-101,-109,-126,-109; D=-12;
/I:         I=-12; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='P';  M= -11,-101, -52, -29, -32, -91, -90, -31,  -8, -97, -92,  12,  50, -83,   9,  39,   1, -15,-105, -18; D=-12;
/I:         I=-12; DM=-13;
/M: SY='Q';  M= -50, -99, -76,  25, -96, -91, -77, -26,  53, -45, -82, -23,  -1,  59,  46,  -3, -30, -57, -95, -26; D=-12;
/I:         I=-12; DM=-13;
/M: SY='P';  M= -16,  11, -90, -82, -81, -43, -89,  39, -28,  25,   8, -89,  93, -85, -90, -81,  -3, -28, -95, -85;
/M: SY='P';  M=  36, -10, -79,  11, -96, -81, -83, -34,  -3, -51, -82, -80,  94,  -5,  -2,  15, -73, -55, -96, -91;
/M: SY='L';  M= -80, -89, -98, -15,   4,-103, -92,  57, -92,  58,   4, -96, -96, -89, -93, -90, -76,  48, -91, -71;
/M: SY='G';  M=  56,  29, -84, -87, -19,  80, -88, -93, -85, -92, -85, -73, -86, -83, -91, -64,   0, -54, -92, -89;
/M: SY='I';  M= -33, -90, -98, -38,  33,-100, -92,  71, -91,  22,  -3, -92, -94, -24, -92, -29, -75,  47, -87,  -7;
/M: SY='I';  M= -82, -89,-102, -97,  15,-104, -91,  67, -95,  60,  -7, -97, -97, -91, -94, -91, -77,  28, -86,  -1;
/M: SY='P';  M= -84,-108, -83, -73,-103, -85, -86, -91, -80,-102, -88,  -8, 129, -83, -92, -80, -76, -97, -97,-100;
/M: SY='L';  M=  27,  54, -92, -90, -72,  25, -86, -11, -88,  63,  10, -21, -94, -85, -39, -78, -23, -66, -93, -79;
/M: SY='G';  M= -67, -94, -82, -94,-100, 106, -89,-108, -87,-104, -93, -68, -86, -85, -95, -67, -86,-102, -91, -95;
/M: SY='T';  M= -68,  17, -76, -78, -85, -44, -82, -81, -75, -85, -80, -66,   0, -76, -31,  54,  99, -74,-100,  -4;
/M: SY='G';  M=  48,  -5,   1, -84, -95,  78, -87, -90, -83, -92, -85, -70, -85, -81, -90, -31,  21, -18, -95, -91;
/M: SY='N';  M= -80, -87,  20, -72, -95, -21,  22, -95, -67,-101, -88, 122, -90, -68, -75, -63, -66, -97,-114, -87;
/M: SY='D';  M=  25,   1, 100, -58, -98, -22, -74, -92, -74, -40, -89,  12, -86,   5, -81, -14, -33, -39,-109, -87;
/M: SY='F';  M= -87, -89,-103, -97,  86,-101, -85,  -6, -95,  62,  20, -97,-101, -94, -92, -93, -82, -28,  36,   0;
/M: SY='A';  M=  84,   3, -83, -79, -90, -22, -85, -80, -80, -37, -78, -76, -85, -76, -85,  46, -11, -14, -96, -87;
/M: SY='R';  M= -34,  -7, -80, -75, -84,   1,  20, -40,   8, -84,  14,  -1, -88, -19,  81, -72,  39, -22,  15,  10;
/M: SY='S';  M=  44,  57, -18, -78, -88, -15, -83, -79, -77, -29, -79, -22, -86,   0, -18,  62,  15,   5,-100, -86;
/M: SY='L';  M=  21,  55, -94, -90,  -7, -92, -87, -11, -89,  62,  26,   0, -96, -86, -90, -80,  -1,  16, -93, -75;
/M: SY='H';  M= -56, -93, -75, -43, -89,  67,  87, -93, -76, -24, -80,  38,  -6, -39,  10, -70,  -5, -39, -98, -22;
/M: SY='W';  M= -82, -98, -99, -91, -67,  16, -95,  55, -89,  24, -65, -93,   5,  15, -91, -87, -83,   6, 121,  -5;
/I:         I=-20; MD=-21;
/M: SY='P';  M= -36,-103, -87, -40,-100,  47, -10, -98, -87,-102, -92, -82,  82, -21, -95,  14,   7, -48,-100, -10; D=-20;
/I:         I=-20; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='Q';  M= -41, -94,  17,  49, -18, -35, -74, -20, -34,  14, -30,  25, -21,  56,  32, -29,  -6, -81, -95, -80;
/M: SY='D';  M= -28, -94,  62,  27, -94, -51,  43, -24,  10, -26, -82,  34,  38,  19, -74,  -2,  -8, -87,-103, -83;
/M: SY='P';  M= -12, -94, -94, -85, -76, -94, -91,  42, -88,  33,  24, -93,  86, -87, -93, -84, -76,  29, -94, -82;
/M: SY='M';  M=  30,  11, -31,  23, -37, -49,  -6,  15, -15,   0,  31, -77,   6, -16, -16,  18,  19, -30, -94, -24;
/M: SY='E';  M= -35, -91,  19,  43, -90, -24, -73, -91,  41, -41, -83,  18, -22,  23, -26,  41,  20, -87, -94,   5;
/M: SY='A';  M=  72,  42, -88, -83, -10, -78, -89,  25, -83, -32, -72, -80, -87, -81, -88,   7,  31,   3, -95, -82;
/M: SY='L';  M=  48, -10, -93, -87, -37, -87, -85, -61, -87,  67,  36, -87, -92, -83, -88, -36,  28, -62, -92, -76;
/M: SY='L';  M=  14, -90,  30,   7, -80, -87,  -4, -74,  14,  44,   9, -29, -88,  29,  28, -23,  -7, -75, -95, -79;
/M: SY='H';  M=  20,  21, -44,   7, -80, -84,  50, -73,   0,  39, -68,  13, -89, -35,   1,  30, -33,  -6, -98, -78;
/M: SY='I';  M=  31, -88, -99, -93, -28, -95, -93,  70, -92,  48, -15, -93, -94, -88, -94, -83, -75,  24, -91, -75;
/M: SY='I';  M= -26,  28,   2,  19, -78, -35, -84,  50, -25,   7,  20,  29, -24, -77, -38, -18,  10,  15, -98, -81;
/M: SY='H';  M=  -5,   6,  -5,  45, -89, -42,  60, -82,  38, -31,  16, -72, -84,  17,  33, -74,  -3,   4, -98, -79;
/M: SY='G';  M=  38, -89, -16, -41, -30,  77, -83, -96, -79, -95, -87,  -4, -16, -78,  -9,  16, -19, -89, -93, -89;
/I:         I=-30; MD=-32;
/M: SY='Q';  M= -52, -98,  25,   4,  -9, -23,  21,  -5,   2, -87,   1,  10,   8,  56,  38,  -1, -21, -51, -98, -81; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='P';  M=  33, -15, -47,  13, -10, -20, -85, -14,   9, -10, -75, -78,  49, -76, -80,   4,  39,   6, -95, -83;
/M: SY='T';  M= -59, -91, -83, -75, -80, -92,  33,  19,  28, -10, -29, -76,  -1,  35,  33, -26,  39,  37, -95, -14;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='P';  M=  29, -92, -47, -50, -21, -83, -14, -40,  20, -20,  21, -79,  73,   1,  15,  14, -73,   1, -93, -35;
/M: SY='M';  M= -79,  30,-101, -96,   2,-102, -92,  55, -93,  45,  60, -94, -96, -90, -93, -88, -31,  48, -92, -72;
/M: SY='D';  M= -85, -98, 117, -50,-100, -82, -69,-102, -71,-100, -97,  -8, -85,   6, -23, -73, -75, -99,-112,  -4;
/M: SY='R';  M=   4, -10, -94, -87, -71, -96, -87,  39, -77,  45,  -5, -88, -94, -81,  49, -82, -11,  41, -94, -77;
/M: SY='W';  M=  15,  38, -97, -91,   5,  32, -93, -17, -88,   7,  48, -88, -26, -86, -91, -13, -82, -14, 122, -67;
/M: SY='Q';  M=  -2,  21, -36,  12, -46, -84, -31, -41,  37, -53, -32, -71, -85,  51,  38,  32,  14, -16,  20, -30;
/M: SY='V';  M=   1,  36, -99, -93,   0, -98, -95,  48, -88,  11,  19, -92, -95, -90, -10, -84, -73,  71, -95, -75;
/M: SY='N';  M= -75, -90,  15,  23, -93,   2,  29, -88,   3, -59,   7,  71,   0,  20, -36,  22,  19, -36,-102, -84;
/I:         I=-30; MD=-32;
/M: SY='Q';  M= -22, -96,  38, -78, -91,  20,  -2, -14, -53, -11,  -7,   1, -93,  38, -25, -28,  23,  11,  15, -86; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='W';  M=  11, -95,  36,  29, -90, -10,  -4, -11,  13, -59, -22,  15,  22,  -1,  38, -73, -11, -84,  51, -29;
/M: SY='N';  M= -47, -10,  -5, -20, -82,  30,  39, -55,   7, -45, -26,  43,  32,  -5, -45,  23,   9, -87, -90,  43;
/I:         E1=0; IE=-105; DE=-105;

» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	201 in 201 different sequences
Number of true positive hits	201 in 201 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	window20
Author [info]	PS_Langendijk_Genevaux
Feature key [info]	DOMAIN
Feature description [info]	DAGKc
Version [info]	5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

201 sequences

AGK_DANRE   (Q7ZW00), AGK_HUMAN   (Q53H12), AGK_MOUSE   (Q9ESW4),

AGK_PONAB   (Q5RED7), AGK_XENLA   (Q7ZYJ3), BMRU_BACSU  (P39074), 
CERK1_HUMAN (Q8TCT0), CERK1_MOUSE (Q8K4Q7), CERKL_HUMAN (Q49MI3), 
CERK_ARATH  (Q6USK2), CERK_CAEEL  (Q9TZI1), CERK_ORYSJ  (C0LT23), 
DAGK_BACSU  (O31502), DAGK_MYCTO  (P9WP28), DAGK_MYCTU  (P9WP29), 
DAGK_STAA1  (A7X424), DAGK_STAA2  (A6U302), DAGK_STAA3  (Q2FFJ7), 
DAGK_STAA8  (Q2FWZ2), DAGK_STAA9  (A5IU64), DAGK_STAAB  (Q2YU29), 
DAGK_STAAC  (Q5HEM4), DAGK_STAAE  (A6QIC6), DAGK_STAAM  (Q99SY8), 
DAGK_STAAN  (Q7A4Q8), DAGK_STAAR  (Q6GFF9), DAGK_STAAS  (Q6G835), 
DAGK_STAAT  (A8Z2R1), DAGK_STAAW  (Q7A0H3), DAGK_STACT  (B9DMT6), 
DAGK_STAEQ  (Q5HN36), DAGK_STAES  (Q8CRU5), DAGK_STAHJ  (Q4L7L1), 
DAGK_STAS1  (Q49YU2), DGK1_ARATH  (Q39017), DGK1_DROME  (Q01583), 
DGK1_ORYSJ  (Q7XQT2), DGK2_ARATH  (Q9FFN7), DGK2_DROME  (Q09103), 
DGK3_ARATH  (Q8VZG1), DGK3_CAEEL  (Q03603), DGK4_ARATH  (Q1PDI2), 
DGK5_ARATH  (Q9C5E5), DGK5_CAEEL  (Q10024), DGK6_ARATH  (F4JKI3), 
DGK7_ARATH  (F4JQ95), DGKA_BOVIN  (A0JN54), DGKA_DICDI  (P34125), 
DGKA_HUMAN  (P23743), DGKA_MOUSE  (O88673), DGKA_PIG(P20192), 
DGKA_RAT(P51556), DGKB_HUMAN  (Q9Y6T7), DGKB_MOUSE  (Q6NS52), 
DGKB_RAT(P49621), DGKD_HUMAN  (Q16760), DGKD_MOUSE  (E9PUQ8), 
DGKE_HUMAN  (P52429), DGKE_MOUSE  (Q9R1C6), DGKG_HUMAN  (P49619), 
DGKG_MOUSE  (Q91WG7), DGKG_RAT(P49620), DGKH_DROAN  (B3LXF2), 
DGKH_DROER  (B3NYS4), DGKH_DROGR  (B4JHJ7), DGKH_DROME  (A8JQ65), 
DGKH_DROMO  (B4K6T8), DGKH_DROSE  (B4I4Y1), DGKH_DROSI  (B4R0A5), 
DGKH_DROYA  (B4PRE2), DGKH_HUMAN  (Q86XP1), DGKH_MESAU  (Q64398), 
DGKH_MOUSE  (D3YXJ0), DGKI_HUMAN  (O75912), DGKI_MOUSE  (D3YWQ0), 
DGKI_RAT(F1MAB7), DGKK_HUMAN  (Q5KSL6), DGKQ_HUMAN  (P52824), 
DGKQ_MOUSE  (Q6P5E8), DGKQ_RAT(D3ZEY4), DGKZ_HUMAN  (Q13574), 
DGKZ_MOUSE  (Q80UP3), DGKZ_RAT(O08560), LCB4_SCHPO  (O14159), 
LCB4_YEAST  (Q12246), LCB5_YEAST  (Q06147), LCBK1_ARATH (Q9LRB0), 
LCKB2_ARATH (O82359), MAMU_MAGGM  (Q6NE47), MAMU_PARM1  (Q2W8P4), 
SPHK1_ARATH (Q8L7L1), SPHK1_CAEEL (Q18425), SPHK1_HUMAN (Q9NYA1), 
SPHK1_MOUSE (Q8CI15), SPHK1_RAT   (Q91V26), SPHK2_ARATH (F2Y4A3), 
SPHK2_HUMAN (Q9NRA0), SPHK2_MOUSE (Q9JIA7), SPHKA_DICDI (Q86KF9), 
SPHKB_DICDI (Q6B516), Y036_SYNY3  (Q55452), Y1045_STRPN (Q97QZ6), 
Y1050_STACT (B9DP10), Y1993_STAS1 (Q49VS2), Y2167_STAHJ (Q4L4E9), 
Y390_STAEQ  (Q5HR05), Y499_MYCTO  (P9WKT8), Y499_MYCTU  (P9WKT9), 
Y507_STAES  (Q8CQ05), Y510_MYCBO  (P64720), Y675_STAAB  (Q2YSK5), 
Y681_STAAN  (Q7A6T6), Y688_STAAW  (Q8NXN1), Y691_STAAS  (Q6GBA4), 
Y695_STAAE  (A6QF35), Y711_STAA3  (Q2FIR4), Y723_STAA1  (A7WZL3), 
Y726_STAAM  (Q99VP7), Y736_STAA8  (Q2G084), Y749_STAA9  (A5IQS9), 
Y749_STAAT  (A8YZZ7), Y766_STAA2  (A6TZK4), Y780_STAAR  (Q6GIR5), 
Y787_STAAC  (Q5HHU6), YEGS_ALCBS  (Q0VSB2), YEGS_CHRSD  (Q1QUK4), 
YEGS_CITK8  (A8AED8), YEGS_CROS8  (A7MHI5), YEGS_ECO24  (A7ZNQ8), 
YEGS_ECO27  (B7UTC1), YEGS_ECO45  (B7MEE4), YEGS_ECO55  (B7L9V9), 
YEGS_ECO57  (Q8X7H7), YEGS_ECO5E  (B5YV36), YEGS_ECO7I  (B7NPP4), 
YEGS_ECO8A  (B7M470), YEGS_ECOBW  (C4ZSH2), YEGS_ECODH  (B1X7I0), 
YEGS_ECOHS  (A8A1V4), YEGS_ECOK1  (A1ACV5), YEGS_ECOL5  (Q0TG03), 
YEGS_ECOL6  (Q8FFZ2), YEGS_ECOLC  (B1IYZ1), YEGS_ECOLI  (P76407), 
YEGS_ECOLU  (B7NCB9), YEGS_ECOSE  (B6HYT0), YEGS_ECOSM  (B1LN99), 
YEGS_ECOUT  (Q1R9Y4), YEGS_ENT38  (A4WCD7), YEGS_ESCF3  (B7LV48), 
YEGS_KLEP3  (B5XPB3), YEGS_PECAS  (Q6D2A2), YEGS_PECCP  (C6DBD7), 
YEGS_PSE14  (Q48GV2), YEGS_PSEAB  (Q02PI7), YEGS_PSEAE  (Q9HZI3), 
YEGS_PSEF5  (Q4K8Y4), YEGS_PSEPF  (Q3K959), YEGS_PSEPK  (Q88L12), 
YEGS_PSESM  (Q87ZA2), YEGS_PSEU2  (Q4ZR90), YEGS_SALA4  (B5EXY0), 
YEGS_SALAR  (A9MKW3), YEGS_SALCH  (Q57MK0), YEGS_SALDC  (B5FMV6), 
YEGS_SALG2  (B5RBY0), YEGS_SALHS  (B4T9V5), YEGS_SALNS  (B4SXX2), 
YEGS_SALPA  (Q5PLT6), YEGS_SALPB  (A9N7J9), YEGS_SALPC  (C0Q0Z4), 
YEGS_SALPK  (B5BF43), YEGS_SALSV  (B4TNJ7), YEGS_SALTY  (Q8ZNP1), 
YEGS_SERP5  (A8GHR8), YEGS_SHEFN  (Q081R7), YEGS_SHIB3  (B2TY99), 
YEGS_SHIDS  (Q32EB4), YEGS_SHIF8  (Q0T347), YEGS_SHIFL  (Q83KI0), 
YEGS_SHISS  (Q3Z0C0), YEGS_STRMK  (B2FKL6), YEGS_VIBPA  (Q87IB3), 
YEGS_XANAC  (Q8PQ53), YEGS_XANC8  (Q4UZH0), YEGS_XANCP  (Q8PD82), 
YEGS_XANE5  (Q3BYC8), YEGS_XANOM  (Q2NYP7), YEGS_XANOR  (Q5GVG9), 
YEGS_YERE8  (A1JKV8), YEGS_YERP3  (A7FG10), YEGS_YERPA  (Q1C5L2), 
YEGS_YERPB  (B2K9M7), YEGS_YERPE  (Q7CJL3), YEGS_YERPG  (A9QZU2), 
YEGS_YERPN  (Q1CK68), YEGS_YERPP  (A4TMR9), YEGS_YERPS  (Q668B9), 
YEGS_YERPY  (B1JSC7), YSM3_CAEEL  (Q10123), YTLR_BACSU  (O34799)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

11 PDB

2BON; 2JGR; 2P1R; 2QV7; 2QVL; 3VZB; 3VZC; 3VZD; 4L02; 4V24; 7CGP