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PROSITE entry PS50141


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50141
Entry name [info] A_DEAMIN_EDITASE
Accession [info] PS50141
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50141
Associated ProRule [info] PRU00240

Name and characterization of the entry

Description [info] Adenosine to inosine editase domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=330;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=325;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.1822000; R2=0.0130667; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=20300.9199219; R2=22.8418484; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=637; H_SCORE=34851; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=484; H_SCORE=31356; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 29 in 29 different sequences
Number of true positive hits 29 in 29 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] DOMAIN
Feature description [info] A to I editase
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
29 sequences

ADAD1_HUMAN (Q96M93), ADAD1_MOUSE (Q5SUE7), ADAD1_RAT   (Q3KR54), 
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PDB
[Detailed view]
12 PDB

1ZY7; 5ED1; 5ED2; 5HP2; 5HP3; 6D06; 6VFF; 7KFN; 8E0F; 8E4X; 9D5J; 9D5K