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PROSITE entry PS50115


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50115
Entry name [info] ARFGAP
Accession [info] PS50115
Entry type [info] MATRIX
Date [info] 01-MAY-2002 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50115
Associated ProRule [info] PRU00288

Name and characterization of the entry

Description [info] ARF GTPase-activating proteins domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=122;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=117;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.9473000; R2=0.0108972; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6979.9799805; R2=6.1108871; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=923; H_SCORE=12620; N_SCORE=11.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=694; H_SCORE=11221; N_SCORE=8.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 109 in 109 different sequences
Number of true positive hits 109 in 109 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] Arf-GAP
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
109 sequences

ACAP1_BOVIN (A5PK26), ACAP1_HUMAN (Q15027), ACAP1_MOUSE (Q8K2H4), 
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PDB
[Detailed view]
22 PDB

1DCQ; 2B0O; 2CRR; 2CRW; 2D9L; 2IQJ; 2OLM; 2P57; 3DWD; 3FEH; 3FM8; 3JUE;
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