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PROSITE entry PS50092


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50092
Entry name [info] TSP1
Accession [info] PS50092
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50092
Associated ProRule [info] PRU00210

Name and characterization of the entry

Description [info] Thrombospondin type-1 (TSP1) repeat profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=53;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=53;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=5.7964869; R2=0.0000896; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=313572.8125000; R2=1.2190678; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=24593; H_SCORE=343553; N_SCORE=8.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=7852; H_SCORE=323145; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: B0=*; B1=*; E0=*; E1=*; MM=*; II=*;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 851 in 247 different sequences
Number of true positive hits 851 in 247 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.88 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 27
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] TSP type-1
Version [info] 7

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
247 sequences

ADT1_CAEEL  (G5ECS8), ADT2_CAEEL  (Q19204), AGRB1_HUMAN (O14514), 
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UniProtKB/Swiss-Prot
False negative sequences
1 sequence

YSM5_CAEEL  (Q10125)

		
PDB
[Detailed view]
80 PDB

1LSL; 1SZL; 1VEX; 1W0R; 1W0S; 2BBX; 2RJQ; 3GHM; 3GHN; 3OJY; 3R6B; 3T5O;
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