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PROSITE entry PS50085


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50085
Entry name [info] RAPGAP
Accession [info] PS50085
Entry type [info] MATRIX
Date [info] 01-APR-2003 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50085
Associated ProRule [info] PRU00165

Name and characterization of the entry

Description [info] Rap GTPase activating proteins domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=217;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=212;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1180999; R2=0.0206674; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2487.7551270; R2=30.5401878; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=382; H_SCORE=14154; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=213; H_SCORE=8993; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-1000; E1=-1000; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 38 in 38 different sequences
Number of true positive hits 38 in 38 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] Rap-GAP
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
38 sequences

GARL3_CHICK (Q5ZJY3), GARL3_DANRE (A5PF44), GARL3_HUMAN (Q5VVW2), 
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PDB
[Detailed view]
4 PDB

1SRQ; 3BRW; 7DL2; 9CE3