PROSITE logo

PROSITE entry PS50081


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50081
Entry name [info] ZF_DAG_PE_2
Accession [info] PS50081
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00379
Associated ProRule [info] PRU00226

Name and characterization of the entry

Description [info] Zinc finger phorbol-ester/DAG-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=51;
/DISJOINT: DEFINITION=PROTECT; N1=2; N2=51;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1802; R2=0.0097; TEXT='NScore';
/CUT_OFF: LEVEL=1; SCORE=652; N_SCORE=8.5; MODE=1; TEXT='!!';
/CUT_OFF: LEVEL=0; SCORE=590; N_SCORE=7.9; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=446; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105;
...
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 391 in 287 different sequences
Number of true positive hits 386 in 282 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 11
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 98.72 %
Recall (true positives / (true positives + false negatives)) 97.23 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 3
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] ZN_FING
Feature description [info] Phorbol-ester/DAG-type
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
282 sequences

AKP13_HUMAN (Q12802), AKP13_MOUSE (E9Q394), AKP13_RAT   (F1M3G7), 
» more

UniProtKB/Swiss-Prot
False negative sequences
11 sequences

DGK2_DROME  (Q09103), DGKI_HUMAN  (O75912), DGKI_MOUSE  (D3YWQ0), 
» more

UniProtKB/Swiss-Prot
False positive sequences
5 sequences

NSE1_BOVIN  (Q3T0X7), NSE1_HUMAN  (Q8WV22), NSE1_MOUSE  (Q9D720), 
» more

PDB
[Detailed view]
79 PDB

1FAQ; 1FAR; 1KBE; 1KBF; 1PTQ; 1PTR; 1R79; 1RFH; 1TBN; 1TBO; 1XA6; 1Y8F;
» more