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PROSITE entry PS50076


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PURL: https://purl.expasy.org/prosite/signature/PS50076

Direct ScanProsite submission
General information about the entry

Entry name [info] DNAJ_2
Accession [info] PS50076
Entry type [info] MATRIX
Date [info] 01-NOV-1997 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00553
Associated ProRule [info] PRU00286; PRU50000

Name and characterization of the entry

Description [info] dnaJ domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=66;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=61;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-1.3380001; R2=0.0152141; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3768.5698242; R2=3.4767442; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=647; H_SCORE=6018; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=516; H_SCORE=5563; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=*; E1=*; MI=-105; MD=-105; IM=-105; DM=-105; MM=1; M0=-3;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 1'246 in 1'246 different sequences
Number of true positive hits 1'239 in 1'239 different sequences
Number of 'unknown' hits 0
Number of false positive hits 7 in 7 different sequences
Number of false negative sequences 48
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 99.44 %
Recall (true positives / (true positives + false negatives)) 96.27 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] DOMAIN
Feature description [info] J
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
1239 sequences

APJ1_YEAST  (P53940), ATCJ_SHEON  (Q8EFW5), AUL1_ARATH  (Q9FWS1), 
» more

UniProtKB/Swiss-Prot
False negative sequences
48 sequences

ARC6_ARATH  (Q9FIG9), AUXI1_ARATH (Q9SU08), AUXI2_ARATH (Q0WQ57), 
» more

UniProtKB/Swiss-Prot
'Partial' sequences
3 sequences

DNAJ1_STRAL (P96457), DNAJ_STRAG  (P95694), DNJC1_CANLF (P82539)

		
UniProtKB/Swiss-Prot
False positive sequences
7 sequences

NAC1_BOVIN  (P48765), NAC1_CANLF  (P23685), NAC1_CAVPO  (P48766), 
» more

PDB
[Detailed view]
94 PDB

1BQ0; 1BQZ; 1FAF; 1FPO; 1GH6; 1HDJ; 1IUR; 1N4C; 1NZ6; 1WJZ; 1XBL; 1XI5;
» more