Swiss Institute of Bioinformatics

ExPASy Proteomics Server

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Entry: PS50056

General information about the entry
Entry name	TYR_PHOSPHATASE_2
Accession number	PS50056
Entry type	MATRIX
Date	NOV-1997 (CREATED); NOV-1997 (DATA UPDATE); JUN-2010 (INFO UPDATE).
PROSITE Documentation	PDOC00323
Name and characterization of the entry
Description	Tyrosine specific protein phosphatases family profile.
Matrix / Profile	/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=68; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=63; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=.7969; R2=.01657001; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=464; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=344; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105; MM=1; M0=-1; A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='E'; M= -9, -3,-21, 0, 5,-18,-20, -6,-15, 1, -6, -7, -6,-13, 1, 2, -8, -7,-13,-25,-10, 2; /M: SY='D'; M= -9, 10,-25, 13, 10,-22,-12, 0,-24, 5,-20,-15, 8,-12, 3, 2, 2, -4,-20,-28,-11, 6; /M: SY='F'; M=-14,-27,-24,-34,-26, 39,-27,-18, 6,-25, 9, 2,-21,-25,-28,-20,-19,-10, 2, 10, 19,-25; /M: SY='L'; M= -6,-22,-21,-24,-16, 2,-26,-18, 13,-19, 14, 8,-19,-20,-15,-16,-14, -6, 11,-20, -3,-16; /M: SY='E'; M= -7, 5,-26, 7, 10,-24,-10, -2,-24, 7,-22,-13, 5, -8, 8, 6, 1, -5,-21,-27,-14, 8; /M: SY='M'; M= -4,-13,-21,-15, -5, -2,-19,-12, -4, -7, 1, 3,-12,-17, -6, -6, -9, -6, -3,-19, -4, -5; /M: SY='V'; M= 1,-24,-12,-27,-23, -2,-27,-24, 19,-19, 11, 8,-22,-24,-21,-19,-10, -1, 24,-25, -7,-22; /M: SY='R'; M=-10, 5,-25, 4, 7,-23,-17, 2,-22, 13,-20, -9, 6,-14, 9, 14, -2, -6,-19,-26,-10, 7; /M: SY='E'; M= -4, 1,-22, -2, 3,-12,-17, -3,-14, -2,-13, -7, 2,-13, 2, -4, 2, 3,-12,-23, -6, 2; /I: MD=-15; /M: SY='I'; M= -6,-19,-13,-23,-17, 4,-24,-14, 7,-15, 5, 4,-16,-21,-15,-13,-10, -4, 7,-16, 1,-16; D=-2; /I: MD=-15; /M: SY='Y'; M=-10, -7,-22, -9, -6, -4,-19, -5, -5, -5, -3, -2, -5,-17, -5, -2, -8, -4, -5,-18, 1, -7; D=-2; /I: MD=-15; /M: SY='E'; M= -6, 3,-19, 4, 9,-22,-12, -5,-20, 6,-19,-12, 2, -1, 5, 4, 0, -4,-18,-24,-15, 6; D=-2; /I: MD=-15; /M: SY='E'; M= -3, -3,-19, -3, 5,-16,-14, -3,-13, 4,-12, -6, -4, -7, 4, 0, -2, -5,-10,-19, -9, 4; D=-2; /I: I=-4; MI=0; MD=-11; IM=0; DM=-11; /M: SY='K'; M= -3, -2,-14, -2, 2,-11, -6, -4,-12, 3, -9, -5, -2, -5, 1, 2, -1, -2, -9,-13, -7, 1; D=-2; /I: DM=-15; /M: SY='S'; M= -4, 2,-19, 1, 3,-21, -9, -1,-21, -1,-19,-11, 3,-12, 4, -2, 5, -1,-17,-28,-11, 3; /M: SY='E'; M= -4, -1,-25, 0, 5,-24,-14, -3,-20, 5,-21,-12, 1, 4, 4, 2, 0, -4,-19,-27,-15, 3; /M: SY='G'; M= -3, 0,-27, 0,-10,-27, 40,-11,-34,-13,-28,-19, 7,-18,-11,-13, 4,-12,-27,-24,-23,-11; /M: SY='P'; M= -5,-10,-14,-10, -5,-24, 0,-13,-24, -4,-22,-14, -6, 4, -7, -5, -3, -8,-19,-28,-21, -8; /I: MD=-21; /M: SY='P'; M= -6, -7,-17, -6, 0,-17,-10, -9,-14, 2,-14, -8, -6, 8, -2, 1, -5, -6,-13,-20,-13, -3; D=-4; /I: I=-5; MI=0; IM=0; DM=-21; /M: SY='I'; M= -4,-27,-18,-32,-26, -1,-32,-27, 30,-24, 15, 13,-22,-21,-22,-23,-14, -3, 28,-24, -5,-26; /M: SY='V'; M= -2,-25,-13,-28,-23, 0,-24,-22, 18,-23, 17, 9,-23,-26,-22,-21,-14, -3, 21,-24, -6,-23; /M: SY='V'; M= -1,-29,-14,-31,-29, 1,-31,-29, 32,-22, 12, 11,-28,-28,-28,-22,-11, -1, 44,-28, -8,-29; /M: SY='H'; M=-19, -1,-29, -1, -1,-19,-20, 94,-28,-10,-20, 0, 9,-20, 9, -1, -9,-18,-28,-29, 19, -1; /M: SY='C'; M=-10,-20,117,-30,-30,-20,-28,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-49,-30,-30; /M: SY='S'; M= 3, -6,-15, -8, -4,-15, -9,-11,-12, -7,-15, -9, 0,-15, -1, -4, 16, 8, -6,-31,-13, -3; /M: SY='A'; M= 30, -4,-11,-11, -8,-20, -1,-13,-13,-10,-12, -9, -4,-13, -9,-17, 6, -2, -5,-24,-18, -9; /M: SY='G'; M= 0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20, 0,-20,-20,-20, 0,-20,-30,-20,-30,-20; /M: SY='V'; M= -3,-24,-14,-28,-22, -4,-27,-21, 19,-20, 10, 8,-20,-24,-18,-18,-12, -4, 21,-25, -6,-22; /M: SY='G'; M= 1, -4,-25, -5,-13,-27, 46,-15,-34,-15,-29,-19, 6,-17,-12,-15, 9,-10,-25,-25,-26,-13; /M: SY='R'; M=-18,-10,-29,-10, 1,-20,-20, -1,-28, 28,-19,-10, 0,-19, 10, 64, -9, -9,-19,-20,-10, 1; /M: SY='T'; M= 6, -1, -8, -7, -6,-15,-11,-16,-14,-10,-18,-14, 3,-10, -6,-11, 27, 35, -4,-34,-15, -6; /M: SY='G'; M= 8,-11,-23,-12,-16,-26, 42,-20,-30,-16,-25,-17, -4,-12,-17,-19, 3,-12,-20,-22,-26,-17; /M: SY='T'; M= 0,-11, -3,-18,-16, -7,-22,-20, 0,-15, -3, -3,-10,-18,-14,-15, 6, 22, 8,-28, -8,-16; /M: SY='F'; M=-12,-29,-20,-34,-26, 35,-30,-19, 15,-26, 20, 11,-24,-28,-28,-20,-20, -8, 13, -7, 15,-26; /M: SY='I'; M= -2,-24, 0,-31,-26, -5,-30,-27, 22,-24, 8, 7,-20,-24,-21,-24,-11, -3, 22,-27, -9,-26; /M: SY='A'; M= 16,-18, -8,-24,-19,-10,-12,-22, 4,-18, 3, 1,-16,-20,-17,-20, -3, -1, 11,-24,-14,-18; /M: SY='I'; M= 8,-21,-12,-27,-19, -5,-22,-21, 13,-19, 11, 8,-18,-21,-16,-19, -9, -4, 12,-23, -9,-19; /M: SY='Y'; M=-12, 1,-25, 5, 0, -4,-18, 3,-17, -8,-11,-10, -5,-19, -6,-10, -8, -9,-16, -4, 14, -4; /M: SY='L'; M= -6,-20,-17,-25,-19, 1,-27,-17, 15,-21, 17, 11,-17,-23,-16,-17,-14, -4, 10,-20, 0,-19; /M: SY='M'; M= -6,-23,-15,-29,-22, -1,-22,-16, 19,-20, 18, 27,-20,-23,-14,-18,-17, -7, 14,-23, -5,-19; /I: I=-5; MI=0; IM=0; DM=-15; MD=-15; /M: SY='E'; M= -6, 4,-25, 4, 14,-21,-12, -4,-20, 2,-18,-13, 3, -8, 4, -2, 1, -2,-19,-25,-11, 8; /M: SY='E'; M= -8, -3,-20, -3, 1,-15,-10, -4,-18, -2,-11, -7, -3,-15, -1, -2, -6, -8,-16,-23, -8, -1; /M: M= -6, -3,-18, -5, -5,-19, -3,-10,-15, -6,-16, -9, 0,-14, -5, -6, -1, -4,-10,-27,-15, -6; /M: SY='I'; M= -8,-26,-16,-29,-22, 6,-29,-21, 19,-20, 16, 14,-23,-25,-20,-17,-17, -7, 19,-17, -1,-21; /M: SY='D'; M= -9, 20,-24, 25, 8,-27, -8, -4,-27, 2,-26,-20, 13,-10, 1, -2, 8, 1,-21,-33,-15, 4; /M: SY='I'; M= -3,-24,-22,-26,-19, -1,-27,-21, 16,-20, 9, 6,-21,-11,-18,-20,-12, -5, 15,-19, -2,-20; /M: M= -9, -4,-23, -6, -1, 0,-16, -6,-15, -5,-10, -9, -3,-13, -7, -4, -7, -8,-15,-17, -1, -4; /M: SY='D'; M= -9, 14,-27, 20, 16,-29, -8, 1,-28, 3,-23,-16, 8, -9, 10, -1, 1, -8,-25,-29,-16, 13; /M: SY='A'; M= 17,-16, -9,-23,-17, -7,-16,-20, 3,-16, 1, 0,-14,-17,-15,-19, 0, 4, 9,-23,-11,-16; /M: SY='V'; M= -7,-27,-19,-31,-26, 8,-31,-21, 24,-21, 15, 12,-24,-27,-22,-18,-16, -5, 26,-15, 6,-26; /M: SY='K'; M= -9, 2,-21, 5, 8,-23,-16, -3,-22, 9,-16,-11, -1,-14, 6, 8, -3, -7,-18,-26,-11, 6; /M: SY='Y'; M= -7,-11,-22,-14, -5, -1,-20, -6, -7, -6, -3, 0, -8,-18, -4, -4, -7, -4, -7,-15, 3, -5; /M: SY='L'; M= -8,-28,-19,-31,-23, 7,-29,-20, 24,-24, 29, 23,-26,-27,-18,-19,-21, -8, 20,-21, -1,-21; /M: SY='R'; M=-17, -7,-29, -7, 4,-22,-20, 0,-28, 29,-21, -9, 0,-17, 12, 53, -9,-10,-20,-20, -9, 4; /M: SY='Q'; M= -5, 1,-23, 1, 5,-21,-16, -1,-17, 4,-15, -7, 1,-14, 8, 3, 1, -1,-14,-26,-10, 6; /M: SY='Q'; M= -7, -5,-22, -6, 3,-21,-19, 2,-18, 8,-15, -4, -3,-16, 17, 11, -4, -8,-17,-20, -5, 9; /M: SY='R'; M=-19, -8,-30, -8, 1,-21,-20, -1,-30, 31,-21,-10, 1,-19, 10, 65,-10,-10,-20,-20,-10, 1; /M: SY='P'; M= -7,-12,-27,-11, -6,-20,-12, -9,-15, -8,-17, -8, -7, 26, -7, -8, -6, -7,-18,-28,-19, -9; /M: SY='G'; M= -3, -4,-25, -8,-13,-18, 27, -6,-23,-14,-19, -9, 5,-20,-10,-13, 0,-11,-21,-22,-15,-12; /M: SY='M'; M= 0,-19,-19,-25,-17, -4,-16,-11, 11,-14, 14, 27,-17,-20, -8,-13,-11, -6, 7,-22, -6,-13; /M: SY='V'; M= -2,-28,-16,-31,-28, 2,-28,-28, 28,-22, 10, 11,-24,-26,-26,-22,-11, -3, 36,-25, -7,-28; /M: SY='Q'; M= -9, -2,-25, -5, 9,-28,-19, 1,-11, 1,-12, -1, 0,-14, 32, 2, -2, -7,-18,-24,-11, 20; /M: SY='T'; M= 0, 0,-14, -5, -4,-17,-13,-12,-14, -7,-15, -9, 1,-11, 0, -7, 17, 29, -7,-30,-12, -2; /M: SY='E'; M=-10, 0,-26, 4, 11,-16,-19, -9,-20, 1,-16,-13, -4, 6, 0, -5, -5, -6,-20,-24,-11, 5; /M: SY='E'; M= -3, 10,-23, 13, 23,-27,-13, -1,-23, 1,-19,-14, 4, -9, 11, -5, 3, -5,-21,-30,-16, 17; /M: SY='Q'; M=-11, -2,-29, -2, 16,-34,-21, 11,-18, 8,-15, 1, -2,-12, 47, 8, -4,-11,-26,-21, -8, 31; /M: SY='Y'; M=-17,-14,-29,-13,-12, 14,-27, 11, -6, -5, -2, -2,-15,-23, -5, -5,-16, -9,-12, 11, 48,-12; /M: SY='Y'; M= -9,-15,-25,-17, -6, -2,-25, -7, 0, -6, -1, 0,-13,-20, -4, -3,-11, -6, -1,-12, 6, -7; /I: E1=0; IE=-105; DE=-105;
Numerical results
UniProtKB/Swiss-Prot release number: 08, total number of sequence entries in that release: 518415. Total number of hits in UniProtKB/Swiss-Prot: 368 hits in 330 different sequences Number of hits on proteins that are known to belong to the set under consideration: 366 hits in 328 different sequences Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences Number of false hits (on unrelated proteins): 2 hits in 2 different sequences Number of known missed hits: 33 Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 27 Precision (true hits / (true hits + false positives)): 99.46 % Recall (true hits / (true hits + false negatives)): 91.73 %
Comments
MATRIX_TYPE: protein_domain Scaling database: UniProtKB/Swiss-Prot: reversed Matrix author: K_Hofmann Taxonomic range: Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses Maximum known number of repetitions of the pattern in a single protein: 2 VERSION: 1
Cross-references
UniProtKB/Swiss-Prot	True positive hits: 123R_IIV6 (O55737), CC14A_HUMAN (Q9UNH5), CC14A_MOUSE (Q6GQT0), CC14B_HUMAN (O60729), CC14B_MOUSE (Q6PFY9), CC14C_HUMAN (A4D256), CC14C_HYLSY (A6N3Q4), CDC14_CAEEL (P81299), CDC14_YEAST (Q00684), CDKN3_HUMAN (Q16667), CSW_DROME (P29349), CSW_DROSI (Q8ISC9), CSW_DROVI (Q24708), DS22A_DANRE (Q1LWL2), DS22B_DANRE (Q566R7), DUPD1_ANOCA (P0C598), DUPD1_BOVIN (P0C591), DUPD1_CALMI (P0C5A2), DUPD1_CHICK (P0C597), DUPD1_DANRE (Q29RA3), DUPD1_GASAC (P0C5A0), DUPD1_HORSE (P0C592), DUPD1_HUMAN (Q68J44), DUPD1_MONDO (P0C593), DUPD1_MOUSE (Q8BK84), DUPD1_ORYLA (P0C5A1), DUPD1_PANTR (P0C594), DUPD1_PIG (P0C596), DUPD1_RAT (P0C595), DUPD1_TAKRU (P0C599), DUPD1_TETNG (Q4RQD3), DUPD1_XENLA (Q4KL92), DUPD1_XENTR (A4IHU7), DUS10_BOVIN (Q0IID7), DUS10_HUMAN (Q9Y6W6), DUS10_MOUSE (Q9ESS0), DUS11_BOVIN (Q5E999), DUS11_HUMAN (O75319), DUS11_MOUSE (Q6NXK5), DUS11_RAT (Q4KM79), DUS12_HUMAN (Q9UNI6), DUS12_MOUSE (Q9D0T2), DUS12_RAT (Q9JIM4), DUS13_HUMAN (Q9UII6), DUS13_MOUSE (Q9QYJ7), DUS14_BOVIN (Q17QM8), DUS14_HUMAN (O95147), DUS14_MOUSE (Q9JLY7), DUS15_HUMAN (Q9H1R2), DUS15_MOUSE (Q8R4V2), DUS16_HUMAN (Q9BY84), DUS18_BOVIN (Q5BIP9), DUS18_HUMAN (Q8NEJ0), DUS18_MOUSE (Q8VE01), DUS18_PONAB (Q5R8X2), DUS18_RAT (Q6AXW7), DUS19_HUMAN (Q8WTR2), DUS19_MOUSE (Q8K4T5), DUS1_HUMAN (P28562), DUS1_MOUSE (P28563), DUS1_RAT (Q64623), DUS21_HUMAN (Q9H596), DUS22_HUMAN (Q9NRW4), DUS22_MOUSE (Q99N11), DUS22_XENLA (Q6GQJ8), DUS22_XENTR (Q5XHB2), DUS23_HUMAN (Q9BVJ7), DUS23_MOUSE (Q6NT99), DUS26_BOVIN (Q17QJ3), DUS26_HUMAN (Q9BV47), DUS26_MOUSE (Q9D700), DUS26_PONAB (Q5R6H6), DUS26_RAT (Q5FVI9), DUS27_HUMAN (Q5VZP5), DUS27_MOUSE (Q148W8), DUS28_HUMAN (Q4G0W2), DUS28_MOUSE (Q8BTR5), DUS2_HUMAN (Q05923), DUS2_MOUSE (Q05922), DUS3_HUMAN (P51452), DUS3_MOUSE (Q9D7X3), DUS3_PONAB (Q5RD73), DUS4_CHICK (Q9PW71), DUS4_HUMAN (Q13115), DUS4_MOUSE (Q8BFV3), DUS4_RAT (Q62767), DUS5_HUMAN (Q16690), DUS5_RAT (O54838), DUS6_BOVIN (Q2KJ36), DUS6_HUMAN (Q16828), DUS6_MOUSE (Q9DBB1), DUS6_RAT (Q64346), DUS7_HUMAN (Q16829), DUS7_MOUSE (Q91Z46), DUS7_RAT (Q63340), DUS8_HUMAN (Q13202), DUS8_MOUSE (O09112), DUS9_HUMAN (Q99956), DUSP1_DICDI (Q55E39), DUSP2_DICDI (Q54R42), DUSP3_DICDI (Q55BI8), DUSP4_DICDI (Q54T76), DUSPR_DICDI (Q556Y8), DUSP_FOWPV (Q9J592), DUSP_MYXVL (Q85297), DUSP_VACCC (P20495), DUSP_VACCW (P07239), DUSP_VAR67 (P33064), EPM2A_CANFA (Q1M199), EPM2A_HUMAN (O95278), EPM2A_MOUSE (Q9WUA5), EPM2A_RAT (Q91XQ2), FLP1_SCHPO (Q9P7H1), HOPD2_PSESM (Q79LY0), IBR5_ARATH (Q84JU4), IPHP_NOSCO (Q05918), LAR_CAEEL (Q9BMN8), LAR_DROME (P16621), MCE1_CAEEL (Q17607), MCE1_HUMAN (O60942), MCE1_MOUSE (O55236), MDSP_HUMAN (Q6B8I1), MDSP_MOUSE (Q6B8I0), MPL1_DICDI (Q55CS7), MPL2_DICDI (Q55CS8), MPL3_DICDI (Q54Y32), MSG5_YEAST (P38590), MTM1_BOVIN (A6QLT4), MTM1_HUMAN (Q13496), MTM1_MOUSE (Q9Z2C5), MTM1_PONAB (Q5R9S3), MTM1_XENLA (Q52KU6), MTM1_XENTR (Q5EB32), MTMR1_HUMAN (Q13613), MTMR1_MOUSE (Q9Z2C4), MTMR2_BOVIN (A6QLT2), MTMR2_CHICK (Q5ZIV1), MTMR2_DANRE (A0JMK5), MTMR2_HUMAN (Q13614), MTMR2_MOUSE (Q9Z2D1), MTMR2_PONAB (Q5REB9), MTMR4_HUMAN (Q9NYA4), MTMR4_MOUSE (Q91XS1), MTMR7_HUMAN (Q9Y216), MTMR7_MOUSE (Q9Z2C9), MTMR7_PONAB (Q5R6F6), PMP1_SCHPO (O13453), PPS1_YEAST (P38148), PTN11_CHICK (Q90687), PTN11_HUMAN (Q06124), PTN11_MOUSE (P35235), PTN11_RAT (P41499), PTN12_HUMAN (Q05209), PTN12_MOUSE (P35831), PTN13_HUMAN (Q12923), PTN13_MOUSE (Q64512), PTN14_HUMAN (Q15678), PTN14_MOUSE (Q62130), PTN18_HUMAN (Q99952), PTN18_MOUSE (Q61152), PTN1_CHICK (O13016), PTN1_HUMAN (P18031), PTN1_MOUSE (P35821), PTN1_RAT (P20417), PTN20_HUMAN (Q4JDL3), PTN20_MOUSE (O55082), PTN20_RAT (A1L1L3), PTN21_HUMAN (Q16825), PTN21_MOUSE (Q62136), PTN21_RAT (Q62728), PTN22_HUMAN (Q9Y2R2), PTN22_MOUSE (P29352), PTN23_HUMAN (Q9H3S7), PTN23_MOUSE (Q6PB44), PTN23_RAT (O88902), PTN2_HUMAN (P17706), PTN2_MOUSE (Q06180), PTN2_RAT (P35233), PTN3_HUMAN (P26045), PTN4_HUMAN (P29074), PTN4_MOUSE (Q9WU22), PTN5_HUMAN (P54829), PTN5_MOUSE (P54830), PTN5_RAT (P35234), PTN6_HUMAN (P29350), PTN6_MOUSE (P29351), PTN6_RAT (P81718), PTN7_HUMAN (P35236), PTN7_MOUSE (Q8BUM3), PTN7_RAT (P49445), PTN9_HUMAN (P43378), PTN9_MOUSE (O35239), PTN9_RAT (Q641Z2), PTP10_DROME (P35992), PTP1_CAEEL (P28191), PTP1_DICDI (P34137), PTP1_NPVOP (O10274), PTP1_YEAST (P25044), PTP2_CAEEL (P28192), PTP2_DICDI (P34138), PTP2_NPVOP (O10273), PTP2_YEAST (P29461), PTP3_CHLMO (Q39491), PTP3_DICDI (P54637), PTP3_YEAST (P40048), PTP4_CAEEL (P34442), PTP61_DROME (Q9W0G1), PTP69_DROME (P16620), PTP99_DROME (P35832), PTPC1_BOVIN (A7E379), PTPC1_DANRE (A1L1R5), PTPC1_HUMAN (A2A3K4), PTPC1_MOUSE (Q6NZK8), PTPH_AMEPV (Q9EMX1), PTPH_MIMIV (Q5UR74), PTPM1_DROME (Q86BN8), PTPM1_HUMAN (Q8WUK0), PTPM1_MOUSE (Q66GT5), PTPM1_RAT (P0C089), PTPN3_MOUSE (A2ALK8), PTPR2_HUMAN (Q92932), PTPR2_MACNE (O02695), PTPR2_MOUSE (P80560), PTPR2_RAT (Q63475), PTPRA_HUMAN (P18433), PTPRA_MOUSE (P18052), PTPRA_RAT (Q03348), PTPRB_HUMAN (P23467), PTPRB_MOUSE (B2RU80), PTPRC_CYPCA (Q9IBD8), PTPRC_HUMAN (P08575), PTPRC_MOUSE (P06800), PTPRC_RAT (P04157), PTPRD_HUMAN (P23468), PTPRD_MOUSE (Q64487), PTPRE_HUMAN (P23469), PTPRE_MOUSE (P49446), PTPRE_RAT (B2GV87), PTPRF_BOVIN (A7MBJ4), PTPRF_DANRE (A4IFW2), PTPRF_HUMAN (P10586), PTPRF_MOUSE (A2A8L5), PTPRF_RAT (Q64604), PTPRG_CHICK (Q98936), PTPRG_HUMAN (P23470), PTPRG_MOUSE (Q05909), PTPRH_HUMAN (Q9HD43), PTPRJ_CHICK (Q9W6V5), PTPRJ_HUMAN (Q12913), PTPRJ_MOUSE (Q64455), PTPRK_HUMAN (Q15262), PTPRK_MOUSE (P35822), PTPRM_HUMAN (P28827), PTPRM_MOUSE (P28828), PTPRN_BOVIN (P56722), PTPRN_HUMAN (Q16849), PTPRN_MOUSE (Q60673), PTPRN_RAT (Q63259), PTPRO_HUMAN (Q16827), PTPRQ_HUMAN (Q9UMZ3), PTPRQ_MOUSE (P0C5E4), PTPRQ_RAT (O88488), PTPRR_HUMAN (Q15256), PTPRR_MOUSE (Q62132), PTPRR_RAT (O08617), PTPRS_HUMAN (Q13332), PTPRS_MOUSE (B0V2N1), PTPRS_RAT (Q64605), PTPRT_HUMAN (O14522), PTPRT_MOUSE (Q99M80), PTPRU_CHICK (Q6YI48), PTPRU_DANRE (B3DK56), PTPRU_HUMAN (Q92729), PTPRU_MOUSE (B1AUH1), PTPRV_MOUSE (P70289), PTPRV_RAT (Q64612), PTPRZ_HUMAN (P23471), PTPRZ_RAT (Q62656), PTPX_CANAL (P43078), PTP_NPVAC (P24656), PVH1_SCHPO (O13632), PVH1_YEAST (Q02256), PYP1_SCHPO (P27574), PYP2_SCHPO (P32586), PYP3_SCHPO (P32587), SDP1_YEAST (P40479), SPTP_SALPA (Q5PEA9), SPTP_SALTI (P74851), SPTP_SALTY (P74873), SSH1_HUMAN (Q8WYL5), SSH1_MOUSE (Q76I79), SSH2_HUMAN (Q76I76), SSH2_MOUSE (Q5SW75), SSH3_HUMAN (Q8TE77), SSH3_MOUSE (Q8K330), SSH3_RAT (Q5XIS1), SSH_DROME (Q6NN85), SSH_XENLA (Q6IVY4), STYXA_XENLA (Q4V7N3), STYXB_XENLA (Q5U593), STYX_HUMAN (Q8WUJ0), STYX_MOUSE (Q60969), STYX_PONAB (Q5RDP3), TP4A1_HUMAN (Q93096), TP4A1_MACFA (Q9TSM6), TP4A1_MOUSE (Q63739), TP4A1_PONAB (Q5R7J8), TP4A1_RAT (Q78EG7), TP4A2_HUMAN (Q12974), TP4A2_MOUSE (O70274), TP4A2_RAT (Q6P9X4), TP4A3_BOVIN (A2VDT1), TP4A3_HUMAN (O75365), TP4A3_MOUSE (Q9D658), TP4AA_DICDI (Q54DU9), TP4AB_DICDI (Q86IL4), VF197_IIV3 (Q196Z3), VF197_IIV6 (Q91FX3), VH01_RACVI (P80994), VHP1_CAEEL (Q10038), Y669_RALEH (P40289), YAV4_XANCP (P0A0W0), YAV4_XANEU (P0A0W1), YK13_CAEEL (P34337), YNBD_ECOLI (P76093), YO42_CAEEL (P34680), YOPH_YEREN (P15273), YOPH_YERPS (P08538) False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile): D1060_DICDI (Q1ZXG8), MTM1_RAT (Q6AXQ4), MTMR3_HUMAN (Q13615), MTMR3_MOUSE (Q8K296), MTMR3_RAT (Q5PQT2), MTMR4_XENLA (Q7ZXF1), MTMR6_HUMAN (Q9Y217), MTMR6_MOUSE (Q8VE11), MTMRC_DANRE (A2BGG1), MTMRC_HUMAN (Q9C0I1), MTMRC_MOUSE (Q80TA6), MTMRC_PONAB (Q5R989), MTMRC_RAT (Q5FVM6), MTMR_DICDI (Q54GQ1), OCA1_ASHGO (Q75B37), OCA1_CANAL (Q59XY9), OCA1_CANGA (Q6FSZ8), OCA1_DEBHA (Q6BLZ8), OCA1_KLULA (Q6CTE4), OCA1_PICGU (A5DE24), OCA1_PICST (A3LW52), OCA1_USTMA (Q4P7L6), OCA1_YARLI (Q6C4X9), OCA1_YEAS7 (A6ZRY1), OCA1_YEAST (P50946), OCA6_YEAST (Q12454), SIW14_YEAST (P53965), STYL1_HUMAN (Q9Y6J8), Y1500_ARATH (Q9ZVN4), Y7071_DICDI (Q550K8), YKCA_CAEEL (P42083), YMR1_YEAST (P47147), YNF3_SCHPO (Q9UUF3) `Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences): PTP10_STYPL (P28202), PTP11_STYPL (P28203), PTP12_STYPL (P28204), PTP13_STYPL (P28205), PTP14_STYPL (P28206), PTP15_STYPL (P28207), PTP16_STYPL (P28208), PTP17_STYPL (P28209), PTP18_STYPL (P28210), PTP19_STYPL (P28211), PTP1_STYPL (P28193), PTP20_STYPL (P28212), PTP21_STYPL (P28213), PTP22_STYPL (P28214), PTP23_STYPL (P28215), PTP24_STYPL (P28216), PTP25_STYPL (P28217), PTP26_STYPL (P28218), PTP27_STYPL (P28219), PTP2_STYPL (P28194), PTP3_STYPL (P28195), PTP4_STYPL (P28196), PTP5_STYPL (P28197), PTP6_STYPL (P28198), PTP7_STYPL (P28199), PTP8_STYPL (P28200), PTP9_STYPL (P28201) False positive hits (sequences which do not belong to the set under consideration): Y215_METJA (Q57668), Y3520_METJA (Q60280) Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
PDB [Detailed view]	1A5Y; 1AAX; 1BZC; 1BZH; 1BZJ; 1C83; 1C84; 1C85; 1C86; 1C87; 1C88; 1ECV; 1EEN; 1EEO; 1FPR; 1FPZ; 1FQ1; 1G1F; 1G1G; 1G1H; 1G4U; 1G4W; 1G7F; 1G7G; 1GFY; 1GWZ; 1I57; 1I9S; 1I9T; 1J4X; 1JF7; 1JLN; 1KAK; 1KAV; 1L8G; 1L8K; 1LAR; 1LQF; 1LYV; 1M3G; 1MKP; 1NL9; 1NNY; 1NO6; 1NWE; 1NWL; 1NZ7; 1OEM; 1OEO; 1OES; 1OET; 1OEU; 1OEV; 1OHC; 1OHD; 1OHE; 1ONY; 1ONZ; 1P15; 1PA1; 1PA9; 1PH0; 1PTT; 1PTU; 1PTV; 1PTY; 1PXH; 1PYN; 1Q1M; 1Q6J; 1Q6M; 1Q6N; 1Q6P; 1Q6S; 1Q6T; 1QXK; 1R6H; 1RPM; 1RXD; 1SUG; 1T48; 1T49; 1T4J; 1V3A; 1VHR; 1WAX; 1WCH; 1WRM; 1X24; 1XBO; 1XM2; 1XXP; 1XXV; 1YFO; 1YGR; 1YGU; 1YN9; 1YPT; 1YTN; 1YTS; 1YTW; 1YZ4; 1ZC0; 1ZCK; 1ZCL; 1ZZW; 2A3K; 2A8B; 2AHS; 2AZR; 2B07; 2B3O; 2B49; 2B4S; 2BGD; 2BGE; 2BIJ; 2BV5; 2BZL; 2C46; 2C7S; 2CFV; 2CJZ; 2CM2; 2CM3; 2CM7; 2CM8; 2CMA; 2CMB; 2CMC; 2CNE; 2CNF; 2CNG; 2CNH; 2CNI; 2E0T; 2ESB; 2F6F; 2F6T; 2F6V; 2F6W; 2F6Y; 2F6Z; 2F70; 2F71; 2FH7; 2FJM; 2FJN; 2G59; 2G6Z; 2GJT; 2GP0; 2GWO; 2H02; 2H03; 2H04; 2H4G; 2H4K; 2H4V; 2HB1; 2HC1; 2HC2; 2HCM; 2HNP; 2HNQ; 2HVL; 2HXP; 2HY3; 2I1Y; 2I3R; 2I3U; 2I42; 2I4E; 2I4G; 2I4H; 2I5X; 2I75; 2IMG; 2J16; 2J17; 2JJD; 2NLK; 2NT2; 2NT7; 2NTA; 2NV5; 2NZ6; 2OC3; 2OOQ; 2OUD; 2P4D; 2P6X; 2PA5; 2PBN; 2PQ5; 2Q05; 2QBP; 2QBQ; 2QBR; 2QBS; 2QCJ; 2QCT; 2QDC; 2QDM; 2QDP; 2QEP; 2R0B; 2RF6; 2SHP; 2VEU; 2VEV; 2VEW; 2VEX; 2VEY; 2WGP; 2ZMM; 2ZN7; 3B7O; 3BLT; 3BLU; 3BM8; 3BRH; 3CM3; 3CWE; 3D42; 3D44; 3D9C; 3EAX; 3EB1; 3EU0; 3EZZ; 3F81; 3F99; 3F9A; 3F9B; 3H2X; 3I7Z; 3I80; 3JRL;

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