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PROSITE entry PS50051


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PURL: https://purl.expasy.org/prosite/signature/PS50051

Direct ScanProsite submission
General information about the entry

Entry name [info] MCM_2
Accession [info] PS50051
Entry type [info] MATRIX
Date [info] 01-NOV-1997 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00662

Name and characterization of the entry

Description [info] MCM family domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=207;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=202;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.1582000; R2=0.0127085; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-17643.1796875; R2=32.5363235; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=932; H_SCORE=12681; N_SCORE=12.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=657; H_SCORE=3733; N_SCORE=8.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 112 in 112 different sequences
Number of true positive hits 112 in 112 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
112 sequences

MC6ZA_XENLA (Q498J7), MC6ZB_XENLA (Q7ZY18), MCM2_ARATH  (Q9LPD9), 
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PDB
[Detailed view]
93 PDB

3F9V; 3JA8; 3JC5; 3JC6; 3JC7; 4FDG; 4R7Y; 5BK4; 5U8S; 5U8T; 5V8F; 5XF8;
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