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PROSITE entry PS50030


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50030
Entry name [info] UBA
Accession [info] PS50030
Entry type [info] MATRIX
Date [info] 01-MAR-2003 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50030
Associated ProRule [info] PRU00212

Name and characterization of the entry

Description [info] Ubiquitin-associated domain (UBA) profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=41;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=37;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.8598000; R2=0.0240971; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1512.5749512; R2=2.1125000; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=318; H_SCORE=2184; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=235; H_SCORE=2009; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 260 in 218 different sequences
Number of true positive hits 260 in 218 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 111
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 70.08 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 3
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] DOMAIN
Feature description [info] UBA
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
218 sequences

ACK_DROME   (Q9VZI2), BRSK1_HUMAN (Q8TDC3), BRSK1_MOUSE (Q5RJI5), 
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UniProtKB/Swiss-Prot
False negative sequences
111 sequences

ACK1_BOVIN  (Q17R13), ACK1_HUMAN  (Q07912), ACK1_MOUSE  (O54967), 
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PDB
[Detailed view]
146 PDB

1DV0; 1F4I; 1IFY; 1OQY; 1Q02; 1QZE; 1VEG; 1VEK; 1VG5; 1WGN; 1WHC; 1WIV;
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