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PROSITE entry PS50023


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PURL: https://purl.expasy.org/prosite/signature/PS50023

Direct ScanProsite submission
General information about the entry

Entry name [info] LIM_DOMAIN_2
Accession [info] PS50023
Entry type [info] MATRIX
Date [info] 01-NOV-1997 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00382
Associated ProRule [info] PRU00125

Name and characterization of the entry

Description [info] LIM domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=61;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=61;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.7028; R2=0.0099; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=586; N_SCORE=8.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=283; N_SCORE=5.5; MODE=1; TEXT='R?';
/DEFAULT: B0=-50; E0=-50; D=-20; I=-20; B1=*; E1=*; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 918 in 402 different sequences
Number of true positive hits 918 in 402 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.67 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 6
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann, CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] LIM zinc-binding
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
402 sequences

ABLM1_HUMAN (O14639), ABLM1_MOUSE (Q8K4G5), ABLM2_HUMAN (Q6H8Q1), 
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UniProtKB/Swiss-Prot
False negative sequences
3 sequences

HEL2_SCHPO  (Q76PD2), HEL2_YEAST  (Q05580), Y2098_DICDI (Q55A66)

		
PDB
[Detailed view]
78 PDB

1A7I; 1B8T; 1CTL; 1CXX; 1G47; 1IBI; 1IML; 1J2O; 1M3V; 1NYP; 1QLI; 1RUT;
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