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PROSITE entry PS50010


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PURL: https://purl.expasy.org/prosite/signature/PS50010

Direct ScanProsite submission
General information about the entry

Entry name [info] DH_2
Accession [info] PS50010
Entry type [info] MATRIX
Date [info] 01-JAN-2002 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00605
Associated ProRule [info] PRU00062

Name and characterization of the entry

Description [info] Dbl homology (DH) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=187; TOPOLOGY=LINEAR;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=182;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.3186; R2=0.01733342; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=415; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=299; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 225 in 218 different sequences
Number of true positive hits 225 in 218 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann, CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] DH
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
218 sequences

ABR_BOVIN   (A6QNS3), ABR_HUMAN   (Q12979), ABR_MOUSE   (Q5SSL4), 
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PDB
[Detailed view]
140 PDB

1BY1; 1DBH; 1F5X; 1FOE; 1KI1; 1KZ7; 1KZG; 1LB1; 1NTY; 1RJ2; 1TXD; 1X86;
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