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PROSITE entry PS50008


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50008
Entry name [info] PIPLC_Y_DOMAIN
Accession [info] PS50008
Entry type [info] MATRIX
Date [info] 01-NOV-1995 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50007
Associated ProRule [info] PRU00271

Name and characterization of the entry

Description [info] Phosphatidylinositol-specific phospholipase Y-box domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=117;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=112;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-1.2648000; R2=0.0161000; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=5478.2622070; R2=12.5467529; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=1; SCORE=607; H_SCORE=13094; N_SCORE=8.5; MODE=1; TEXT='!!';
/CUT_OFF: LEVEL=0; SCORE=545; H_SCORE=12316; N_SCORE=7.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=483; H_SCORE=11538; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=0; E1=0; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 76 in 76 different sequences
Number of true positive hits 72 in 72 different sequences
Number of 'unknown' hits 0
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 94.74 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] DOMAIN
Feature description [info] PI-PLC Y-box
Version [info] 8

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
72 sequences

PIP1_DROME  (P25455), PIPA_DROME  (P13217), PLC1_CANAX  (O13433), 
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UniProtKB/Swiss-Prot
False positive sequences
4 sequences

ATAB2_MAIZE (B4FTR7), FTSQ_ALLVD  (D3RVH9), MTGA_XYLFA  (Q9PCR3), 
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PDB
[Detailed view]
31 PDB

1DJG; 1DJH; 1DJI; 1DJW; 1DJX; 1DJY; 1DJZ; 1QAS; 1QAT; 2FJU; 2ISD; 2ZKM;
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