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PROSITE entry PS01333


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PURL: https://purl.expasy.org/prosite/signature/PS01333

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General information about the entry

Entry name [info] PYRASE_GLU
Accession [info] PS01333
Entry type [info] PATTERN
Date [info] 01-JUL-1999 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC01036
Associated ProRule [info] PRU10076

Name and characterization of the entry

Description [info] Pyrrolidone-carboxylate peptidase glutamic acid active site.
Pattern [info]
G-x(2)-[GAP]-x(4)-[LIV]-[ST]-x-E-[KR]-[LIVC]-[AG]-x-[NG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 136 in 136 different sequences
Number of true positive hits 135 in 135 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 16
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.26 %
Recall (true positives / (true positives + false negatives)) 89.40 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
135 sequences

PCP1_CALS4  (Q8RBX8), PCP1_PHOLL  (Q7MAZ1), PCP1_SACS2  (P58201), 
» more

UniProtKB/Swiss-Prot
False negative sequences
16 sequences

PCP1_RALN1  (Q8XXE9), PCP2_RALN1  (Q8XT56), PCP2_STRPN  (Q97NG9), 
» more

UniProtKB/Swiss-Prot
False positive sequences
1 sequence

HIS6_COREF  (Q8FNZ9)

		
PDB
[Detailed view]
19 PDB

1A2Z; 1AUG; 1IOF; 1IOI; 1IU8; 1X10; 1X12; 1Z8T; 1Z8W; 1Z8X; 2DF5; 2EO8;
» more