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PROSITE entry PS01331


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS01331
Entry name [info] THYMIDYLATE_KINASE
Accession [info] PS01331
Entry type [info] PATTERN
Date [info] 01-JUL-1999 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC01034

Name and characterization of the entry

Description [info] Thymidylate kinase signature.
Pattern [info] 
[LIV]-[LIVMGSTC]-[DET]-[RH]-[FYHCS]-x(2)-S-[GSTNP]-x-[AVC]-[FY]-[STANQ].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 461 in 461 different sequences
Number of true positive hits 452 in 452 different sequences
Number of 'unknown' hits 0
Number of false positive hits 9 in 9 different sequences
Number of false negative sequences 168
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 98.05 %
Recall (true positives / (true positives + false negatives)) 72.90 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 452 sequences 

KTHY1_SACS2 (Q9UXG7), KTHY1_SULTO (Q975E6), KTHY_ACAM1  (B0C3N6),
» more

UniProtKB/Swiss-Prot
False negative sequences		 168 sequences 

CMPK2_HUMAN (Q5EBM0), CMPK2_MOUSE (Q3U5Q7), KTHY2_SACS2 (P58157),
» more

UniProtKB/Swiss-Prot
False positive sequences		 9 sequences 

GSA_HALWD   (Q18ES5), MANA_ASPNC  (A2QKT4), MDTB_MUSP7  (C6CAI2),
» more

PDB
[Detailed view]		 105 PDB

1E2D; 1E2E; 1E2F; 1E2G; 1E2Q; 1E98; 1E99; 1E9A; 1E9B; 1E9C; 1E9D; 1E9E;
» more