PROSITE entry PS01278

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PURL: https://purl.expasy.org/prosite/signature/PS01278

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General information about the entry

Entry name [info]	MTTASE_RADICAL
Accession [info]	PS01278
Entry type [info]	PATTERN
Date [info]	01-NOV-1997 CREATED; 01-DEC-2001 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00984

Name and characterization of the entry

Description [info]	Methylthiotransferase radical SAM domain signature.
Pattern [info]	[LIVM]-x-[LIVMT]-x(2)-G-C-x(3)-C-[STAN]-[FY]-C-x-[LIVMT]-x(4)-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	1'060 in 1'060 different sequences
Number of true positive hits	1'034 in 1'034 different sequences
Number of 'unknown' hits	0
Number of false positive hits	26 in 26 different sequences
Number of false negative sequences	21
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	97.55 %
Recall (true positives / (true positives + false negatives))	98.01 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	1034 sequences AMTAB_ARCFU (O29021), AMTAB_METJA (Q58277), AMTAB_METTH (O26914), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	21 sequences BCHR_CHLTE (Q8KCU0), MIAB_ANADE (Q2IKE9), MIAB_ANADF (A7HAH8), » more
UniProtKB/Swiss-Prot False positive sequences	26 sequences FOM3_STRWE (Q56184), Y1155_METJA (Q58555), Y1287_METMA (Q8PXD4), » more
PDB [Detailed view]	2 PDB 2QGQ; 4JC0