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PROSITE entry PS01209


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PURL: https://purl.expasy.org/prosite/signature/PS01209

Direct ScanProsite submission
General information about the entry

Entry name [info] LDLRA_1
Accession [info] PS01209
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00929

Name and characterization of the entry

Description [info] LDL-receptor class A (LDLRA) domain signature.
Pattern [info]
C-[VILMA]-x(5,6)-C-[DNH]-x(3)-[DENQHT]-C-x(3,4)-[STADEW]-[DEH]-[DE]-
x(1,5)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 828 in 166 different sequences
Number of true positive hits 827 in 165 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 15
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.88 %
Recall (true positives / (true positives + false negatives)) 98.22 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 31
Site [info] disulfide at position 1
Site [info] disulfide at position 4
Site [info] disulfide at position 8
Site [info] disulfide at position 14
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
165 sequences

AEGP_HUMAN  (Q6UXC1), AEGP_MOUSE  (A2AJA7), AEGP_RAT(Q63191), 
» more

UniProtKB/Swiss-Prot
False negative sequences
15 sequences

ALK_HUMAN   (Q9UM73), ALK_MOUSE   (P97793), GLU2B_BOVIN (Q28034), 
» more

UniProtKB/Swiss-Prot
False positive sequences
1 sequence

MYCB2_DANRE (F1RD40)

		
PDB
[Detailed view]
128 PDB

1AJJ; 1CR8; 1D2J; 1D2L; 1F5Y; 1F8Z; 1J8E; 1LDL; 1LDR; 1N7D; 1V9U; 1XFE;
» more