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PROSITE entry PS01185


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General information about the entry

Entry name [info] CTCK_1
Accession [info] PS01185
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-NOV-1997 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00912

Name and characterization of the entry

Description [info] C-terminal cystine knot signature.
Pattern [info] 
C-C-x(13)-C-x(2)-[GN]-x(12)-C-x-C-x(2,4)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 48 in 48 different sequences
Number of true positive hits 48 in 48 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 33
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 59.26 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 2
Site [info] disulfide at position 4
Site [info] disulfide at position 8
Site [info] disulfide at position 10
Site [info] disulfide at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 48 sequences 

CCN1_CHICK  (P19336), CCN1_HUMAN  (O00622), CCN1_MOUSE  (P18406), 

CCN1_PANTR  (A5A6L1), CCN1_RAT(Q9ES72), CCN2_BOVIN  (O18739), 
CCN2_HUMAN  (P29279), CCN2_MOUSE  (P29268), CCN2_PIG(O19113), 
CCN2_RAT(Q9R1E9), CCN3_CHICK  (P28686), CCN3_COTJA  (P42642), 
CCN3_HUMAN  (P48745), CCN3_MOUSE  (Q64299), CCN3_RAT(Q9QZQ5), 
CCN4_HUMAN  (O95388), CCN4_MOUSE  (O54775), CCN4_RAT(Q99PP0), 
GPHA2_MOUSE (Q925Q5), GPHA2_RAT   (Q925Q4), HMCT_BOMMO  (P98092), 
MUC19_BOVIN (P98091), MUC19_HUMAN (Q7Z5P9), MUC19_MOUSE (Q6PZE0), 
MUC2L_RAT   (P98089), MUC2_HUMAN  (Q02817), MUC2_MOUSE  (Q80Z19), 
MUC5A_HUMAN (P98088), MUC5B_HUMAN (Q9HC84), MUCAP_PIG   (P12021), 
MUCB1_XENLA (P38565), NDP_BOVIN   (Q2KI78), NDP_HUMAN   (Q00604), 
NDP_MACFA   (Q60HE4), NDP_MOUSE   (P48744), SLIT1_HUMAN (O75093), 
SLIT1_MOUSE (Q80TR4), SLIT1_RAT   (O88279), SLIT2_HUMAN (O94813), 
SLIT2_MOUSE (Q9R1B9), SLIT3_HUMAN (O75094), SLIT3_MOUSE (Q9WVB4), 
SLIT3_RAT   (O88280), SLIT_DROME  (P24014), VWF_CANLF   (Q28295), 
VWF_HUMAN   (P04275), VWF_MOUSE   (Q8CIZ8), VWF_PIG (Q28833)
» more

UniProtKB/Swiss-Prot
False negative sequences		 33 sequences 

BURS_AEDAE  (P85316), BURS_ANOGA  (Q66Q82), BURS_APIME  (A2VB89), 

BURS_BOMMO  (Q566B1), BURS_CULPP  (P85315), BURS_DROME  (Q9VD83), 
BURS_MANSE  (Q4FCM6), CCN3_XENLA  (P51609), CCN6_HUMAN  (O95389), 
CER1_CHICK  (Q9PWB0), CER1_HUMAN  (O95813), CER1_MOUSE  (O55233), 
CER1_XENLA  (P70041), CER1_XENTR  (Q07G34), PBURS_ANOGA (Q566B3), 
PBURS_APIME (A2VB90), PBURS_BOMMO (Q566B2), PBURS_DROME (Q9VJS7), 
SOSD1_CHICK (Q6VYA3), SOSD1_HUMAN (Q6X4U4), SOSD1_MOUSE (Q9CQN4), 
SOSD1_PONAB (Q5R5D2), SOSD1_RAT   (Q642G2), SOST_BOVIN  (Q9BG79), 
SOST_CHLAE  (Q9BG78), SOST_HUMAN  (Q9BQB4), SOST_MOUSE  (Q99P68), 
SOST_RAT(Q99P67), SSPO_BOVIN  (P98167), SSPO_CHICK  (Q2PC93), 
SSPO_HUMAN  (A2VEC9), SSPO_MOUSE  (Q8CG65), SSPO_RAT(Q700K0)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

BURS_PERAM  (P84118), VWF_BOVIN   (P80012)


				
	

	

		PDB
[Detailed view]		
		
			9 PDB
			


			4MY2; 4NT5; 5BPU; 5BQ8; 5BQB; 5BQC; 5BQE; 5CL1; 7QCU