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PROSITE entry PS01180


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PURL: https://purl.expasy.org/prosite/signature/PS01180

Direct ScanProsite submission
General information about the entry

Entry name [info] CUB
Accession [info] PS01180
Entry type [info] MATRIX
Date [info] 01-NOV-1997 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00908
Associated ProRule [info] PRU00059

Name and characterization of the entry

Description [info] CUB domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=113;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=110;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.4270475; R2=0.0141260; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6357.4711914; R2=6.2621794; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=501; H_SCORE=9495; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=360; H_SCORE=8612; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-100; E1=-100; MI=-210; MD=-210; IM=0; DM=0;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 608 in 206 different sequences
Number of true positive hits 608 in 206 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 14
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.75 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 27
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann, P_Bucher
Feature key [info] DOMAIN
Feature description [info] CUB
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
206 sequences

AGRB3_HUMAN (O60242), AGRG6_DANRE (C6KFA3), AGRG6_HUMAN (Q86SQ4), 
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UniProtKB/Swiss-Prot
False negative sequences
14 sequences

AGRB3_MOUSE (Q80ZF8), ATS13_HUMAN (Q76LX8), ATS13_MOUSE (Q769J6), 
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PDB
[Detailed view]
57 PDB

1NT0; 1NZI; 1SFP; 1SPP; 1SZB; 2QQK; 2QQL; 2QQM; 2QQO; 2WNO; 3DEM; 3KQ4;
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