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PROSITE entry PS01047


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS01047
Entry name [info] HMA_1
Accession [info] PS01047
Entry type [info] PATTERN
Date [info] 01-NOV-1995 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00804

Name and characterization of the entry

Description [info] Heavy-metal-associated domain.
Pattern [info] 
[LIVNS]-x-{L}-[LIVMFA]-x-C-x-[STAGCDNH]-C-x(3)-[LIVFG]-{LV}-x(2)-[LIV]-
x(9,11)-[IVA]-x-[LVFYS].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 222 in 153 different sequences
Number of true positive hits 207 in 138 different sequences
Number of 'unknown' hits 0
Number of false positive hits 15 in 15 different sequences
Number of false negative sequences 63
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 93.24 %
Recall (true positives / (true positives + false negatives)) 76.67 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 6
Site [info] metal(?) at position 6
Site [info] metal(?) at position 9
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 138 sequences 

ATCS_SYNE7  (P37279), ATCS_SYNY3  (P73241), ATCU1_RHIME (P58341),
» more

UniProtKB/Swiss-Prot
False negative sequences		 63 sequences 

ATOX1_ARATH (Q94BT9), ATOX1_DICDI (Q54PZ2), ATU1_YEAST  (P38360),
» more

UniProtKB/Swiss-Prot
False positive sequences		 15 sequences 

CSPL7_ORYSJ (Q6YT98), CYC6_GRATL  (Q6B941), CYC6_LIMMA  (P00118),
» more

PDB
[Detailed view]		 92 PDB

1AFI; 1AFJ; 1AW0; 1CC7; 1CC8; 1CPZ; 1FD8; 1FE0; 1FE4; 1FEE; 1FES; 1FVQ;
» more