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PROSITE entry PS00973


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00973
Entry name [info] USP_2
Accession [info] PS00973
Entry type [info] PATTERN
Date [info] 01-JUN-1994 CREATED;
01-DEC-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00750
Associated ProRule [info] PRU10093

Name and characterization of the entry

Description [info] Ubiquitin specific protease (USP) domain signature 2.
Pattern [info] 
[YMF]-x-[LK]-x-[SAGNC]-[LIVMFT]-x(2)-H-x-G-x(4,6)-G-H-[YF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 299 in 299 different sequences
Number of true positive hits 299 in 299 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 28
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 91.44 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 13
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 299 sequences 

CREB_ASPCL  (A1CIL1), CREB_ASPFC  (B0Y4P5), CREB_ASPFN  (B8NSV5),
» more

UniProtKB/Swiss-Prot
False negative sequences		 28 sequences 

CYLD_BOVIN  (Q1RMU2), CYLD_HUMAN  (Q9NQC7), CYLD_MOUSE  (Q80TQ2),
» more

PDB
[Detailed view]		 152 PDB

1NB8; 1NBF; 1VJV; 2AYN; 2AYO; 2F1Z; 2GFO; 2HD5; 2IBI; 2Y5B; 2Y6E; 3I3T;
» more