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PROSITE entry PS00972


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PURL: https://purl.expasy.org/prosite/signature/PS00972

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General information about the entry

Entry name [info] USP_1
Accession [info] PS00972
Entry type [info] PATTERN
Date [info] 01-JUN-1994 CREATED;
01-DEC-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00750
Associated ProRule [info] PRU10092

Name and characterization of the entry

Description [info] Ubiquitin specific protease (USP) domain signature 1.
Pattern [info] 
G-[LIVMFY]-x(1,3)-[AGCY]-[NASMQG]-x-C-[FYWC]-[LIVMFCA]-[NSTAD]-[SACV]-x-
[LIVMSF]-[QF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 298 in 298 different sequences
Number of true positive hits 298 in 298 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 29
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 91.13 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 298 sequences 

CREB_ASPCL  (A1CIL1), CREB_ASPFC  (B0Y4P5), CREB_ASPFN  (B8NSV5),
» more

UniProtKB/Swiss-Prot
False negative sequences		 29 sequences 

U17L1_HUMAN (Q7RTZ2), U17L2_HUMAN (Q6R6M4), U17L3_HUMAN (A6NCW0),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

UBP11_CANLF (Q01988)


				
	

	

		PDB
[Detailed view]		
		
			149 PDB
			


			pdb_00001nb8; pdb_00001nbf; pdb_00001vjv; pdb_00002ayn; pdb_00002ayo; pdb_00002f1z; pdb_00002gfo; pdb_00002hd5; pdb_00002ibi; pdb_00002vhf; pdb_00002y5b; pdb_00002y6e; 
			
			

			» more