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PROSITE entry PS00860


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00860
Entry name [info] GTP_CYCLOHYDROL_1_2
Accession [info] PS00860
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00672

Name and characterization of the entry

Description [info] GTP cyclohydrolase I signature 2.
Pattern [info] 
[SA]-x-[RK]-x-Q-[LIVMT]-Q-E-[RNAK]-[LIM]-[TSNV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 310 in 310 different sequences
Number of true positive hits 308 in 308 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 65
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.35 %
Recall (true positives / (true positives + false negatives)) 82.57 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 308 sequences 

GCH11_NOSS1 (Q8YLL1), GCH11_PSEAE (Q9HYG8), GCH11_PSEPK (Q88LV4),
» more

UniProtKB/Swiss-Prot
False negative sequences		 65 sequences 

FOLKE_LACLA (Q9CGE3), FOLKE_LACLM (Q8GJP4), GCH1_ACET2  (A3DHH6),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

GCH1_BACPU  (P48063)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
EME2_XENTR  (Q0IHN5), HOT_DROME   (Q9W265)


				
	

	

		PDB
[Detailed view]		
		
			23 PDB
			


			1A8R; 1A9C; 1FB1; 1FBX; 1GTP; 1IS7; 1IS8; 1N3R; 1N3S; 1N3T; 1WPL; 4DU6; 
			
			

			» more