PROSITE entry PS00832

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General information about the entry

Entry name [info]	25A_SYNTH_1
Accession [info]	PS00832
Entry type [info]	PATTERN
Date [info]	01-OCT-1993 CREATED; 01-DEC-2004 DATA UPDATE; 27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00653

Name and characterization of the entry

Description [info]	2'-5'-oligoadenylate synthases signature 1.
Pattern [info]	G-S-x-[AG]-[KRN]-x-T-x-L-[KRN]-x(3)-[DE]-x-[DET]-[LM]-[VI]-x-F.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.

Total number of hits	16 in 13 different sequences
Number of true positive hits	16 in 13 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	4
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	80.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	3
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

13 sequences

OAS1A_MOUSE (P11928), OAS1A_RAT   (Q05961), OAS1_HUMAN  (P00973),

OAS1_PIG(Q29599), OAS2_HUMAN  (P29728), OAS2_MOUSE  (E9Q9A9), 
OAS2_RAT(Q5MYU0), OAS3_HUMAN  (Q9Y6K5), OAS3_MOUSE  (Q8VI93), 
OAS3_RAT(Q5MYT7), OASL2_MOUSE (Q9Z2F2), OASL2_RAT   (Q5MYT9), 
OASL_HUMAN  (Q15646)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
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UniProtKB/Swiss-Prot
False negative sequences

4 sequences

OAS1B_MOUSE (Q60856), OAS2_BOVIN  (F1N3B8), OASL1_MOUSE (Q8VI94),

OASL1_RAT   (G3V645)

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PDB
[Detailed view]

8 PDB

1PX5; 4IG8; 4RWN; 4RWO; 4RWP; 4RWQ; 4S3N; 4XQ7