PROSITE entry PS00767

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00767
Entry name [info]	THF_DHG_CYH_2
Accession [info]	PS00767
Entry type [info]	PATTERN
Date [info]	01-DEC-1992 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00616

Name and characterization of the entry

Description [info]	Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2.
Pattern [info]	P-[GK]-G-[VI]-G-P-[MFI]-T-[IVA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	601 in 601 different sequences
Number of true positive hits	600 in 600 different sequences
Number of 'unknown' hits	0
Number of false positive hits	1
Number of false negative sequences	220
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	99.83 %
Recall (true positives / (true positives + false negatives))	73.17 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	600 sequences C1TC_DROME (O96553), C1TC_HUMAN (P11586), C1TC_MOUSE (Q922D8), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	220 sequences FOLD1_DEIGD (Q1J118), FOLD1_DESHY (Q24ZZ6), FOLD1_ECTM1 (A4XTZ3), » more
UniProtKB/Swiss-Prot False positive sequences	1 sequence MTD2L_CALJA (F6ZFR0)
PDB [Detailed view]	31 PDB 1A4I; 1B0A; 1DIA; 1DIB; 1DIG; 3L07; 3NGL; 3NGX; 3P2O; 5O22; 5O28; 5O2A; » more