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PROSITE entry PS00766


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00766
Entry name [info] THF_DHG_CYH_1
Accession [info] PS00766
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00616

Name and characterization of the entry

Description [info] Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1.
Pattern [info] 
[EQLT]-x-[EQKDS]-[LIVM](2)-x(2)-[LIVM]-x(2)-[LIVMY]-N-x-[DNS]-x(5)-
[LIVMF](3)-Q-[LM]-P-[LVI].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 413 in 413 different sequences
Number of true positive hits 413 in 413 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 404
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 50.55 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 413 sequences 

C1TC_DROME  (O96553), C1TC_HUMAN  (P11586), C1TC_MOUSE  (Q922D8),
» more

UniProtKB/Swiss-Prot
False negative sequences		 404 sequences 

FOLD1_ACIAD (Q6F9E6), FOLD1_ARATH (A2RVV7), FOLD1_COLP3 (Q47ZE0),
» more

PDB
[Detailed view]		 27 PDB

1A4I; 1B0A; 1DIA; 1DIB; 1DIG; 3L07; 3P2O; 4A5O; 5O22; 5O28; 5TC4; 6DE8;
» more